Method of treating or ameliorating skin conditions with a magnetic dipole stabilized solution
Inventors
Lange, Peter • Denomme, Brian • Van Wyk, Henk • Van Wyk, Mariette • KREBS, Tracy L. • Ozgur, Sezgin • Haroon, Zishan
Assignees
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Publication Number
US-11202798-B2
Publication Date
2021-12-21
Expiration Date
Abstract
The present invention is directed to methods for treating or ameliorating skin conditions, diabetic conditions, cardiovascular conditions, cancer, infections or metal poisoning, enhancing performance, or providing nutritional support, comprising administering to a subject in need thereof compositions comprising a magnetic dipole stabilized solution (MDSS). The MDSS solution may include additional components and can be provided in a kit.
Core Innovation
A composition is formed by mixing contents of a first vial with contents of a second vial in a 1:1 ratio. The first vial contains an aqueous solution comprising water for injection (WFI), ascorbic acid, thiamine HCl, magnesium sulfate, cyanocobalamin, a B-vitamin, pyridoxine HCl, riboflavin-5′-phosphate, calcium D-pantothenate, and sodium chloride. The second vial contains an aqueous solution comprising WFI, sodium bicarbonate, and sodium chloride.
At least one of the aqueous solutions in at least one of the first vial or the second vial further comprises an antibiotic, and the composition has defined electrical potential characteristics after mixing. The aqueous solution in the first vial has an electrical potential of +1000 to +1300 prior to mixing, and the aqueous solution in the second vial has an electrical potential of +5 to +700 prior to mixing. After mixing, the composition has an electrical potential of −1 to +200.
The mixed composition further has specified weight-percent ranges for ascorbic acid, thiamine HCl, magnesium sulfate, cyanocobalamin, a B-vitamin, pyridoxine HCl, riboflavin 5′-phosphate, calcium D-pantothenate, sodium bicarbonate, and sodium chloride, together with the antibiotic after mixing. The described formulations and concepts are associated with administration for treating or ameliorating skin conditions, conditions associated with diabetes, cardiovascular conditions, cancer, infections, metal poisoning, and providing nutrition support.
Claims Coverage
The independent claim set centers on one two-vial mixing composition with defined pre-mixing and post-mixing electrical potentials and specified composition ranges, with an optional antibiotic. The inventive features are centered on the 1:1 mixing system, the specified aqueous solutions, and the weight-percent ranges for the mixed composition.
Two-vial 1:1 mixing composition
A composition comprising the product of mixing contents of a first vial with contents of a second vial in a 1:1 ratio, wherein the first vial contains an aqueous solution comprising water for injection (WFI), ascorbic acid, thiamine HCl, magnesium sulfate, cyanocobalamin, a B-vitamin, pyridoxine HCl, riboflavin-5′-phosphate, calcium D-pantothenate, and sodium chloride; and the second vial contains an aqueous solution comprising water for injection (WFI), sodium bicarbonate, and sodium chloride.
Antibiotic inclusion after mixing
At least one of the aqueous solutions in at least one of the first vial or the second vial further comprises an antibiotic, wherein the antibiotic is present after mixing.
Pre-mixing electrical potentials with defined post-mixing electrical potential
The aqueous solution in the first vial has an electrical potential of +1000 to +1300 prior to mixing, and the aqueous solution in the second vial has an electrical potential of +5 to +700 prior to mixing, wherein the composition has an electrical potential of −1 to +200.
Specified weight-percent composition ranges for key components
The composition has 4.047% to 4.947% by weight of the ascorbic acid, 0.285% to 0.349% by weight of the thiamine HCl, 3.636% to 4.444% by weight of the magnesium sulfate, 0.0085% to 0.011% by weight of the cyanocobalamin, 0.5345% to 0.6535% by weight of the B-vitamin, 0.5345% to 0.6535% by weight of the pyridoxine HCl, 0.012% to 0.014% by weight of the riboflavin 5′-phosphate, 0.013% to 0.016% by weight of the calcium D-pantothenate, 2.10% to 6.30% by weight of the sodium bicarbonate, and 0.0009% to 0.0011% by weight of the sodium chloride, with the antibiotic after mixing.
Across the independent composition claim and its dependents, the coverage centers on a two-vial 1:1 mixing system that yields a composition with defined pre-mixing and post-mixing electrical potentials, includes specified vitamin/mineral and sodium bicarbonate/sodium chloride constituents with defined weight-percent ranges, and optionally includes an antibiotic.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Treating or ameliorating skin conditions.
Treating or ameliorating a condition associated with diabetes.
Treating or ameliorating a condition associated with cardiovascular dysfunction.
Treating or ameliorating cancer.
Treating or ameliorating an infection.
Treating or ameliorating symptoms of menopause.
Treating or ameliorating metal poisoning, including reducing the amount of metal and increasing metal excretion.
Enhancing performance of a subject.
Providing nutrition support.
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