Method and apparatus for providing a quantitative volumetric map of an organ or an assessment of organ health

Inventors

Kelly, MatthewBrady, MichaelHaramija, Marija

Assignees

Perspectum Ltd

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Publication Number

US-11200974-B2

Patent

Publication Date

2021-12-14

Expiration Date


Abstract

A method of providing a quantitative volumetric assessment of organ health or a quantitative map of an organ. The method comprises obtaining a volumetric map of organ health comprising information defining a state of tissue health across at least part of an organ, receiving an input defining at least one organ section, determining an assessment organ volume based at least partly on the at least one defined organ section, calculating an organ-viability measure for the assessment organ volume based at least partly on information within the volumetric map defining the state of tissue health across the organ volume, and outputting an indication of the organ-viability measure.

Core Innovation

The invention provides a quantitative volumetric assessment of organ health by obtaining a volumetric map of organ health that includes information defining a state of tissue health across at least part of an organ. The volumetric model of organ health is aligned to a functional model, and the approach supports section-based evaluation by using the functional organ model to define functional sections and related parts.

The method receives an input from a user defining at least one organ section, where the section relates to a part of a functional section defined by a functional organ model. Based at least partly on the defined organ section, the method determines an assessment organ volume and calculates an organ-viability measure or a measure of the state for the assessment organ volume from the volumetric map.

The method outputs an indication of the organ-viability measure or the measure of the state. The documented overview additionally frames the invention as a non-invasive pre-intervention assessment for organ interventions, including liver resection and non-resection interventions, and as supporting a need beyond volume-only assessment.

Claims Coverage

The document includes three independent claims covering a functional-model-aligned quantitative volumetric assessment of organ health, a quantitative volumetric map of an organ with a state-of-tissue-health measure for a user-defined section, and an apparatus configured to perform the method steps and output an indication.

Functional-model-aligned volumetric organ-health map

obtaining a volumetric map of organ health comprising information defining a state of tissue health across at least part of an organ and aligning the volumetric model of organ health to a functional model

User-defined organ section tied to functional model

receiving an input from a user defining at least one organ section, said section relating to a part of a functional section defined by a functional organ model

Assessment organ volume determination from section

determining an assessment organ volume, based at least partly on the at least one defined organ section

Organ-viability/state calculation from tissue-health information in volumetric map

calculating an organ-viability measure for the assessment organ volume, based at least partly on information within the volumetric map defining the state of tissue health across the organ volume

Output of an indication of the organ-viability measure

outputting an indication of the organ-viability measure

Apparatus configured to perform volumetric organ-health assessment

an apparatus comprising at least one processing component and at least one memory element, arranged to obtain the volumetric map, receive an input defining at least one organ section, determine an assessment organ volume, calculate an organ-viability measure, and output an indication

Across the independent claims, coverage centers on aligning a quantitative volumetric map of tissue health to a functional organ model, receiving user-defined organ sections tied to that functional model, determining an assessment organ volume, calculating a viability or state measure from the volumetric tissue-health information, and outputting an indication; an apparatus claim provides a corresponding processing-and-memory implementation.

Stated Advantages

Non-invasive pre-intervention assessment for organ interventions, including liver resection and non-resection interventions.

Supports a need beyond volume-only assessment.

Documented Applications

Organ interventions, including liver resection and non-resection interventions.

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