System and method for planning and performing a repeat interventional procedure
Inventors
Kruecker, Jochen • Yan, Pingkun • Tahmasebi Maraghoosh, Amir Mohammad • Pinto, Peter A • Wood, Bradford Johns
Assignees
Koninklijke Philips NV • US Department of Health and Human Services
Publication Number
US-11051902-B2
Publication Date
2021-07-06
Expiration Date
2036-08-10
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Abstract
A system for planning and performing a repeat interventional procedure includes a registration device (116) and an image generation device (120) which map current targets in a reference image (104) for a first interventional procedure to at least one guidance image (112) acquired from a different imaging modality. Biopsy locations are recorded to the guidance images during the first interventional procedure and the biopsy locations are mapped to the reference image to provide a planning image for use in a subsequent interventional procedure on the patient. In a subsequent interventional procedure, the prior planning image (124) may be registered to a current reference image (126) and the prior biopsy locations and prior and current targets are mapped to a guidance image acquired from a different imaging modality. Biopsy locations are then mapped to the guidance image (115) and mapped back to the current reference image.
Core Innovation
The invention provides a system and method for planning and performing repeat interventional procedures by registering current targets in a reference image to guidance images acquired from a different imaging modality. The system records biopsy locations and additional relevant information during an initial interventional procedure on the guidance images and maps these locations back to the reference image, thereby creating a planning image for subsequent procedures. This facilitates visualization and tracking of biopsy targets and locations over time.
During a subsequent interventional procedure, the system registers prior planning images, including the mapped biopsy locations and targets, to a current reference image. This composite is then registered to current guidance images to create enhanced guidance images that include prior and current biopsy locations, targets, and associated diagnostic information. The system further records new biopsy locations and relevant data during the current procedure and updates an enhanced planning image for future use.
The problem addressed by the invention is the challenge of accurately localizing and tracking biopsied targets and biopsy locations over multiple repeat interventional procedures, particularly in organs such as the prostate. Traditional methods rely on random sampling without effective lesion targeting, often resulting in repeated sampling of benign tissue and missed detection of cancerous regions. Existing imaging methods, such as MRI and ultrasound guidance, do not efficiently transfer spatial biopsy findings between procedures to allow for targeted and informed repeat biopsies.
Claims Coverage
The patent includes two main independent system claims and one independent method claim, each describing inventive features related to registration, integration, and visualization of biopsy targets, biopsy locations, and associated pathological information across different imaging modalities and over repeat interventional procedures.
Registration of reference images with prior biopsy data to real-time guidance images
The system registers a reference image including target areas and multiple prior biopsy locations with diagnostic pathology results to a series of real-time guidance images acquired from a different imaging modality, generating enhanced guidance images that allow real-time visualization of targets, prior biopsy locations, and pathology during the interventional procedure.
Registration and display of prior planning images and current reference images for repeat procedures
The system stores prior planning images including prior targets and biopsies, registers them to a current reference image with current targets, and further registers real-time enhanced guidance images to the current reference image. This enables the display of mapped current reference images and enhanced planning images incorporating both prior and current procedural data.
Encoding and visualization of pathology and biopsy information within images
The system encodes diagnostic pathology results such as suspicion levels, histopathological findings, anatomical locations, and timing related to biopsy locations into images using visual markers like colors or symbols for enhanced interpretation during planning and intervention.
Workstation integration including memory, processing, interface, and display
The system integrates storage, processing, image registration modules, image generation modules, user interface, and display devices within a workstation to manage images, targets, prior biopsy data, and real-time guidance images for planning and performing repeat interventional procedures.
Method for systematic data registration and visualization during repeat interventional procedures
The method comprises retrieving reference and real-time guidance images from different modalities, registering target areas and prior biopsy markers to generate mapped guidance images, performing interventional procedures with location recording, registering biopsy locations back to reference images, and generating and displaying planning and enhanced planning images incorporating pathology data for repeat interventions.
In summary, the claims cover a system and method that facilitate multi-modal image registration, tracking, and visualization of current and prior biopsy targets and locations along with diagnostic pathology information to improve planning and execution of repeat interventional procedures.
Stated Advantages
The system permits tracking of specific tissue areas over repeat interventional procedures, improving the accuracy and effectiveness of biopsies.
Enables visualization of prior biopsy locations and targets alongside current imaging to allow targeted and efficient sampling, reducing repeated sampling of benign regions.
Utilizes registration between high-resolution reference images and real-time guidance images from different modalities, offering improved visualization for procedure planning and guidance.
Allows incorporation and display of additional diagnostic and histopathological information within the imaging data to assist clinical decision making.
Supports user interaction, input, and dynamic updating of biopsy data and targets during procedures, enhancing procedural flexibility and accuracy.
Documented Applications
Planning and performing biopsy procedures, particularly prostate biopsies, using combined MRI and ultrasound imaging modalities.
Repeat interventional procedures on biological systems, including tissues and tumors, where tracking and targeting of regions over multiple procedures is required.
Applicable to internal evaluation procedures of any solid organ tissue or enhancing structures of the body such as lungs, liver, brain, uterus, gastro-intestinal tract, excretory organs, blood vessels.
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