Wound stasis dressing for large surface wounds
Inventors
Assignees
Publication Number
US-11020279-B2
Publication Date
2021-06-01
Expiration Date
2032-02-16
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Abstract
Embodiments herein provide hemostatic compositions comprising a plurality of liquid-expandable articles arranged on a backing material. In general, embodiments include methods for treating hemorrhagic injuries. More specifically, there is provided a method to effect rapid hemostatic response and control hemorrhage by introducing a hemostatic composition into a bleeding wound cavity. An embodiment also provides a method of preparing or manufacturing such a hemostatic composition.
Core Innovation
The invention provides hemostatic compositions comprising a plurality of liquid-expandable articles arranged on a backing material. These articles are designed to rapidly expand upon contact with a liquid, such as blood, and fill an irregular wound cavity to effect rapid hemostatic response and control hemorrhage. The composition can be introduced into a bleeding wound cavity, where the expandable articles expand to conform to the wound geometry, exert gentle mechanical pressure, and interact with blood components to facilitate clot formation without the need for external compression.
Current wound dressings are insufficient for large, irregular soft tissue wounds because many are too stiff or fail to conform to the wound cavity to stop bleeding effectively. Granular or powder hemostatic products have significant drawbacks including risks of emboli, difficulty in deployment under austere conditions, migration from the wound site, and problems with handling and removal. The invention addresses these issues by employing a dressing with liquid-expandable articles that are pliable, rapidly expanding, and able to fill complex wound cavities, thereby overcoming limitations of existing products.
Claims Coverage
The patent includes one independent claim covering a method of treating a bleeding wound using a hemostatic composition comprising backing material and liquid-expandable articles attached thereto.
Hemostatic composition comprising a pliable backing material with liquid-expandable articles
The hemostatic composition comprises a continuous, pliable sheet of backing material with a plurality of compressed sponge liquid-expandable articles attached at one end to the backing surface and extending away from it.
Attachment and arrangement of liquid-expandable articles on the backing material
Each liquid-expandable article has a first end attached to the backing material and a second opposing end extending away; the articles are attached in a predetermined and substantially coplanar arrangement, with adhesives used for attachment.
Inclusion of therapeutic agents and markers
One or more therapeutic agents or hemostatic agents may be coupled to the backing or liquid-expandable articles; markers such as radiopaque materials or RFID tags may be included on articles or backing to facilitate location and removal.
Use of expanded articles to fill and conform to wound cavities
Upon introduction and expansion, the articles at least partially fill the bleeding wound cavity conforming to its shape, with articles possibly being disposed on both sides of the backing material.
Backing material properties
The backing material may be porous (e.g., fabric, mesh, or gauze) and sufficiently pliable to conform to the wound, enhancing applicability and effectiveness.
The claims focus on the method of using a hemostatic dressing composed of a pliable backing with attached compressed liquid-expandable sponge articles that expand upon contact with liquid to fill a wound cavity and induce hemostasis, including features of therapeutic agent incorporation, marking, article arrangement, and backing material properties.
Stated Advantages
Rapid expansion of the liquid-expandable articles allows quick filling of wound cavities and fast hemostatic effect.
Soft and pliable expanded articles conform to irregular, deep wound geometries providing gentle multidirectional pressure without compromising tissue perfusion.
The design improves wound cavity positioning and tissue apposition, maintaining the dressing in place amid high flow bleeding and patient movement.
The expandable articles can pass through narrow wound openings and spread into crevices, improving hemostasis in complex wounds.
The backing material can be separately removed without disturbing expanded articles, facilitating wound inspection and dressing replacement.
Documented Applications
Treatment of severe hemorrhagic injuries in large soft tissue wounds such as in the calf, thigh, buttocks, or shoulder.
Use in battlefield or traumatic accident scenarios where rapid hemorrhage control is critical.
Application in wounds associated with arterial or venous punctures or lacerations where controlling bleeding effectively is essential.
Provision of a hemostatic dressing that can be applied directly into wound cavities to improve clot formation and reduce blood loss.
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