Portable drug mixing and delivery device and associated methods

Inventors

Standley, Adam R. • Stepanian, Christopher J. • Constantineau, Cole • Bruehwiler, Michel • Buchine, Brent • Chagnon, Jeffrey Thomas • Brik, Robert

Assignees

Windgaplegacyco LLC

Abstract

A portable auto-injector configured to store a dry medication separately from a liquid component, wherein removal of a cap operates a first actuation mechanism which opens a valve between a first and second chamber that are slidably movable relative to each other and thus allows for the initiation of a mixing step prior to injection. An extendable needle guard is provided over the delivery assembly which prevents premature injection as well as inadvertent sticks or other cross contamination of a needle. The needle guard can also form part of a secondary trigger mechanism which injects the mixed components after the mixing stage is complete.

Core Innovation

The invention provides a drug mixing system for a portable auto-injector/drug mixing-and-delivery device that stores a first medicament component in a first chamber and a second medicament component in a second chamber. A housing has the first and second chambers disposed therein, with at least one chamber slidably movable relative to the other, and a valve disposed between the first and second chambers to control communication between the chambers.

An actuation device having a pre-loaded energy source is provided in direct mechanical communication with the valve. The actuation device is configured to allow the valve to alternate between a closed and open state in a first actuation stage, where activating the actuation device allows one of the chambers to slidably move relative to the other within the housing during the first actuation stage. This arrangement enables mixing or reconstitution of the medicament components prior to delivery, using staged actuation that separates the mixing stage from a subsequent injection stage.

The system further includes a first displacement mechanism disposed in the first chamber and in mechanical communication with the actuation device, where the pre-loaded energy drives chamber sliding through the displacement mechanism. Embodiments described include needle guard or needle shield with lockout and secondary trigger operation, and septum-based needle penetration to prevent premature leakage or cross contamination.

Claims Coverage

The independent claims cover a drug mixing system having a housing with first and second chambers that are slidably movable, a valve between the chambers, and an actuation device with a pre-loaded energy source that mechanically operates the valve and causes chamber sliding in a first actuation stage. The claims further include a medicament component arrangement and a first displacement mechanism in mechanical communication with the actuation device, and one independent claim additionally requires a delivery assembly fluidly communicating with the second chamber.

Across the independent claims, the inventive focus is the mechanically coupled combination of a valve between a slidably movable first chamber and second chamber and an actuation device with a pre-loaded energy source that opens the valve in a first actuation stage to allow sliding within the housing, together with a first displacement mechanism mechanically communicated to the actuation device and a specified medicament component arrangement. In one independent claim, the system also includes a delivery assembly configured for fluid communication with the second chamber.

Stated Advantages

Documented Applications