System and method for measuring blood flow parameters in a blood vessel having an endovascular prosthesis

Inventors

KURAGUNTLA, David • Gupta, Samit Kumar • Lau, Lilip • Flannery, Anthony F.

Assignees

Alio Inc

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Publication Number

US-11006845-B2

Patent

Publication Date

2021-05-18

Expiration Date


Abstract

Systems and methods for remotely monitoring blood flow that include an endovascular prosthesis. The endovascular prosthesis includes a conduit forming a lumen within a surrounding wall having an inner surface and an outer surface. A monitoring device is disposed on the wall forming the lumen. The monitoring device comprises a sensor element configured to detect a physical event and to generate an electrical parameter shift in response to the physical event. An antenna portion is configured to receive a first oscillating electrical signal from an interrogator device and to transmit a second oscillating electrical signal to the interrogator device. The second oscillating electrical signal is modulated by the electrical parameter shift.

Core Innovation

The invention relates to an endovascular prosthesis for implantation in a blood vessel that includes a conduit forming a lumen within a surrounding wall having an inner surface and an outer surface. A monitoring device is disposed on the wall forming the lumen, and the monitoring device comprises a sensor element configured to detect blood flow parameters in the blood vessel and generating an electrical parameter shift in response to the blood flow parameters.

The monitoring device further includes an antenna portion configured to receive a first oscillating electrical signal from an interrogator device and to transmit a second oscillating electrical signal to the interrogator device. The second oscillating electrical signal is modulated by the electrical parameter shift, so the interrogator device can determine blood-flow or occlusion levels based on the modulation.

At least one component of the monitoring device is integrated within a structure of the endovascular prosthesis, and the sensor element is an integrated sensor element comprising a first metallic conduit, a second metallic conduit, and a sensor material. The sensor element forms at least a portion of a wire or strut element configured to form the wall structure of the endovascular prosthesis, where the sensor element is formed as a coaxial capacitor with capacitance changing in response to pressure or stress, or as a variable resistor with resistance varying in response to pressure or stress.

Claims Coverage

The independent claim clm-00001 provides broad coverage of an endovascular prosthesis with an integrated sensor-based modulation of an interrogator-derived oscillating signal. The dependent claims refine the monitoring/communication approach by adding an RFID identifier mechanism and by specifying alternative sensor-controlled oscillator types and sensor material implementations, while also constraining prosthesis wall structures and antenna portion implementation.

Endovascular prosthesis with integrated sensor-modulated interrogator signal

An endovascular prosthesis comprising a conduit forming a lumen within a surrounding wall, and a monitoring device disposed on the wall, the monitoring device including a sensor element configured to detect blood flow parameters and generate an electrical parameter shift, and an antenna portion configured to receive a first oscillating electrical signal from an interrogator device and transmit a second oscillating electrical signal modulated by the electrical parameter shift.

Integrated sensor element formed within wall wire or strut

At least one component of the monitoring device is integrated within a structure of the endovascular prosthesis, and the sensor element is an integrated sensor element comprising a first metallic conduit, a second metallic conduit, and a sensor material, where the sensor element forms at least a portion of a wire or strut element configured to form the wall structure.

Coaxial capacitor or variable resistor sensor material responding to pressure or stress

The sensor element is formed as a coaxial capacitor where the sensor material changes in capacitance when subject to pressure or stress, or the sensor element is formed as a variable resistor where the sensor material is disposed between the first metallic conduit and the second metallic conduit and varies in resistance when subject to pressure or stress.

RFID identifier transmission mechanism based on interrogator oscillating signal

An RFID detection mechanism in which the endovascular prosthesis transmits a device identifier when powered by a first electrical oscillating signal.

Passive resonant circuit sensor-controlled oscillator with capacitance-driven modulation

A sensor-controlled oscillator implemented as a passive resonant circuit in which sensor-induced capacitance changes vary the modulated frequency of a second oscillating electrical signal.

Resistor-controlled oscillator with resistance-driven modulation

A sensor-controlled oscillator implemented as a resistor-controlled oscillator in which sensor-induced resistance change varies the modulated frequency of a second oscillating electrical signal.

Monitoring device disposed on specified wall structures

An endovascular prosthesis whose wall is formed using one or more specified structural types (including coaxially disposed rings, a helix, a braided structure, a coil structure, or a structure of interconnected struts) with a monitoring device disposed on the wall forming the lumen.

Metal portion functioning as antenna portion

A configuration in which a metallic portion of the endovascular prosthesis functions as the antenna portion of a monitoring device.

Overall, the claim set covers an endovascular prosthesis having an integrated monitoring device where a sensor detects blood flow parameters and produces an electrical parameter shift that modulates a second oscillating electrical signal transmitted to an interrogator device. Dependent claims further specify an RFID identifier transmission mechanism, alternate sensor-controlled oscillator implementations (passive resonant circuit with capacitance modulation, resistor-controlled oscillator with resistance modulation), alternative sensor responses via coaxial capacitor or variable resistor structures, and particular prosthesis wall construction forms and antenna portion implementation.

Stated Advantages

Provides a monitoring device that detects blood flow parameters and modulates an interrogator-derived oscillating electrical signal.

Enables communication of blood-flow or occlusion levels by modulating a second oscillating electrical signal for interrogation.

Supports integration of monitoring device components within the endovascular prosthesis structure.

Documented Applications

Remote blood-flow monitoring using an endovascular prosthesis with an integrated monitoring device and an interrogator device to determine blood-flow or occlusion levels.

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