Dry powder inhaler

Inventors

Lastow, Orest

Assignees

Iconovo AB

Abstract

A dry powder inhaler may include at least one air inlet, at least one air outlet, an air channel between said air inlet and outlet, and at least one medicament reservoir. The inhaler may include a dosage mechanism for arranging at least one dose of a medicament from said medicament reservoir between the air channel and the air outlet such that said at least one dose may be delivered upon inhalation at said air outlet. The dosage mechanism may include a dose disc with at least one cavity, wherein the dose disc may be rotatable between a dose collecting position, in which the cavity may be positioned in the medicament reservoir, and a dose administering position, in which the cavity may lie underneath the air channel. The inhaler may also include a floor disc abutting the dose disc underneath the cavity to form a bottom of the cavity for radial emptying of the medicament from the cavity during inhalation. Alternatively, the inhaler may include a floor disc abutting the dose disc underneath the cavity to form a bottom of the cavity and support the medicament in the cavity, wherein said dose disc may rotate in relation to the floor disc when the dose disc is rotated between the dose collecting position and the dose administering position to grind any residual medicament in the cavity.

Core Innovation

The invention concerns a dry powder inhaler that delivers a medicament dose upon inhalation at an air outlet using at least two air inlets and at least two air channels extending between the air inlets and the air outlet. The inhaler includes at least one medicament reservoir and a dosage mechanism arranged to place at least one dose of medicament between the air channel and the air outlet. The dosage mechanism includes a dose disc with at least one cavity that is rotatable between a dose collecting position and a dose administering position.

In the dose collecting position, the cavity is positioned in the medicament reservoir to collect the medicament, and in the dose administering position, the cavity lies underneath one of the air channels. The dosage mechanism further includes a mixing and deaggregation chamber between the air channels and a conduit extending distally from the mixing and deaggregation chamber towards the air outlet. A floor disc abutting the dose disc underneath the cavity forms a bottom of the cavity for radial emptying of the medicament from the cavity during inhalation.

The invention additionally includes an upper proximal reservoir housing with an inhalation chimney that interconnects the conduit and the air outlet, where the inhalation chimney cooperates with the conduit to rotate the dose disc when the upper proximal reservoir housing is rotated. In an embodiment, the floor disc and the dose disc rotate relative to each other when the dose disc is rotated between the dose collecting position and the dose administering position, so that residual medicament in the cavity is ground.

Claims Coverage

The independent claims define a dry powder inhaler with five inventive features combining cavity-based medicament handling with mixing/deaggregation flowpath architecture.

Across the independent claims, the inventive concept is implemented by rotating a cavity-containing dose disc between a reservoir pickup position and an air-channel dispensing position, using a floor disc to provide a cavity bottom for radial emptying, and routing flow through a mixing and deaggregation chamber and a distally extending conduit to the air outlet. Rotation of the dose disc is coupled to the upper proximal reservoir housing via an inhalation chimney, and one independent claim further specifies relative disc-to-floor rotation to grind residual medicament.

Stated Advantages

Documented Applications