Measuring device and methods for use therewith
Inventors
Harding, Ian • Iyengar, Sridhar G. • Wei, Baoguo • Diamond, Steven • Forest, Martin
Assignees
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Publication Number
US-10983083-B2
Publication Date
2021-04-20
Expiration Date
Abstract
The ability to switch at will between amperometric measurements and potentiometric measurements provides great flexibility in performing analyses of unknowns. Apparatus and methods can provide such switching to collect data from an electrochemical cell. The cell may contain a reagent disposed to measure glucose in human blood.
Core Innovation
The invention provides an apparatus for use with a reaction cell having a first electrode, a second electrode, and a third electrode. The apparatus includes a voltage or current source providing a controllable voltage or current to the first electrode, a voltmeter, an amplifier, amperometric circuitry, and switching means configured to float two of the first, second, and third electrodes with respect to circuitry outside of the reaction cell.
The switching means is further configured to isolate the first electrode from a feedback path of the amplifier, to isolate the second electrode from the amperometric circuitry, and to isolate the third electrode from the output of the amplifier. This isolation is performed while the electrodes are floated with respect to circuitry outside of the reaction cell.
A system is described for switching between amperometric and potentiometric measurements using the same type of reaction cell and supporting measurement electronics. The system includes the voltage or current source, voltmeter, amplifier, amperometric circuitry, and switching means arranged to float two of the electrodes relative to circuitry outside of the reaction cell while isolating the first electrode, second electrode, and third electrode from the specified amplifier and amperometric signal paths.
Claims Coverage
The partial content provides two independent claims. Both claims focus on a core measurement architecture using a three-electrode reaction cell with controllable voltage/current drive, an amplifier-based measurement path, amperometric circuitry, a voltmeter, and switching means that float and isolate electrodes from specific feedback and output paths, enabling switching between amperometric and potentiometric measurements.
Electrode floating with switching means
Switching means configured to float two of the first, second and third electrodes with respect to circuitry outside of the reaction cell.
Isolation of electrode from amplifier feedback, amperometric circuitry, and amplifier output
Switching means configured to isolate the first electrode from a feedback path of the amplifier, the second electrode from the amperometric circuitry, and the third electrode from the output of the amplifier.
System switching between amperometric and potentiometric measurements
A system for switching between amperometric and potentiometric measurements including a reaction cell comprising first, second, and third electrodes, with voltmeter, amplifier, amperometric circuitry, and switching means configured to float two of the first, second and third electrodes with respect to circuitry outside of the reaction cell.
Across the independent claims, the inventive coverage centers on floating two of the three reaction-cell electrodes relative to external circuitry and isolating each electrode from specific amplifier feedback, amperometric circuitry, and amplifier output paths. In the system claim, these switching and isolation functions are tied to switching between amperometric and potentiometric measurements.
Stated Advantages
Documented Applications
Implementation in a glucose/blood-chemistry test instrument using a reaction cell for electrochemical measurement with switching between amperometric and potentiometric modes.
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