Methods and systems for analyte information processing
Inventors
Krishnan, Rajaram • CLARK, Iryna • Turner, Robert • Kovelman, Robert • HINESTROSA SALAZAR, Juan Pablo • Liu, David
Assignees
Interested in licensing this patent?
MTEC can help explore whether this patent might be available for licensing for your application.
Publication Number
US-10818379-B2
Publication Date
2020-10-27
Expiration Date
Abstract
Systems, devices, media, methods, and kits are disclosed to integrate and exchange information of analyte analysis kits. Analyte analysis can be performed and presented using in association with advertising or questions.
Core Innovation
The invention describes a portable analyte assay ecosystem integrating a mobile computing device with a cartridge-based analyte analysis apparatus. The mobile device includes a camera positioned to capture an image of a result field of an analyte analysis cartridge, where the cartridge receives and processes biological material of an individual and generates an optical signal based on an analyte. The system performs data analysis on the captured image to generate a result.
The system presents the generated result on the mobile computing device display while incorporating selectable targeted advertisements or survey questions. One or more ads are selected from a population of ads or one or more questions are selected from a population of questions to be presented during at least one of the analyte testing or the data analysis before presenting the result, and the result is locked until the one or more ads have been presented or the one or more questions have been answered.
The system targets the ads or questions based on at least the biological assay and optionally in combination with user profile information, the analyte, a prior analyte testing result, or a location of the mobile computing device. User responses are stored in and update a user profile, and the system supports uploading assay results to an online database with secure HIPAA-compliant encrypted storage and authorization-controlled access.
The invention further includes machine-learning-driven treatment and healthcare-provider recommendations generated using a machine learning algorithm together with inputs including the user profile, the analyte or test results, the device location, cohort historical treatment outcome data for matched patient cohorts, and healthcare provider data. The document discusses data-analysis algorithms for image processing and calibration, and includes examples such as lung cancer monitoring and malaria population monitoring.
Claims Coverage
The provided excerpt contains four independent claims, all sharing a core workflow: capture an optical result field image from a cartridge-based analyte assay with a mobile device camera, perform pixel image data analysis to generate a result, and present the result only after targeted ads or questions are presented and answered. Targeting is based on the biological assay and optionally user profile, analyte, prior result, and device location.
Mobile device-guided cartridge analyte assay with camera image capture
A mobile computing device and an analyte analysis apparatus configured to reversibly accept and position the mobile computing device and an analyte analysis cartridge such that the camera is positioned to capture an image of a result field of the analyte analysis cartridge, wherein the cartridge receives and processes biological material of an individual.
Application module controlling assay, capturing optical signal image, and image processing on pixel data
An application comprising a software module controlling the analyte analysis apparatus to carry out the biological assay by performing analyte testing using the analyte analysis cartridge to generate an optical signal and to control the camera to capture the image of the optical signal in the result field; and a software module performing data analysis on the image to generate a result, wherein the data analysis comprises performing image processing on pixel image data.
Targeted ads/questions workflow with result locked until presented or answered
A software module selecting one or more ads from a population of ads or one or more questions from a population of questions to present during at least one of the analyte testing or the data analysis before presenting the result, wherein the result is locked until the one or more ads have been presented or the one or more questions have been answered.
Targeting of ads/questions using assay and optionally user profile, prior result, and device location
The one or more ads or one or more questions are targeted to the individual based on at least the biological assay and optionally in combination with one or more of a user profile, the analyte, a prior analyte testing result, or a location of the mobile computing device; and user information is updated based on at least the result of the analyte testing.
Non-transitory computer-readable media creating the application for mobile assay
Non-transitory computer readable storage media encoded with a program including instructions executable by at least one processor of a mobile computing device to create an application comprising communicating with the analyte analysis apparatus, transmitting control signals for analyte testing, capturing an image of a result field, performing image processing on pixel image data to generate a result, presenting the result on a display, and selecting targeted ads or questions with the result locked until presented or answered.
User profile update from responses
Responses to the one or more ads or one or more questions are stored in a user profile.
Across the independent claims, the inventive combination is a mobile device using its camera to capture an optical result field image from a cartridge-based analyte assay, followed by image processing on pixel image data to generate and present an assay result, while integrating a targeted ads or questions selection step that locks the result until the ads or questions are presented and answered, with targeting based on assay-related and optionally profile and location data, and with user information updated based on the result.
Stated Advantages
Secure HIPAA-compliant encrypted storage and authorization-controlled access.
Documented Applications
Lung cancer monitoring.
Malaria population monitoring.
Interested in licensing this patent?