Needleless injection device with an angularly-positionable closure stopper
Inventors
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Assignees
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CrossjectCrossject is a specialty pharmaceutical company focused on drug-device combination products for emergency medicine. Leveraging a proprietary needle-free auto-injection platform, the company develops and manufactures fast-acting treatments for life-threatening situations such as epilepsy, adrenal crisis, and anaphylaxis. Crossject conducts advanced regulatory development, clinical validation, and large-scale industrialization to deliver innovative therapies for global markets, with an emphasis on simplicity, reliability, and patient usability.
Crossject is a specialty pharmaceutical company focused on drug-device combination products for emergency medicine. Leveraging a proprietary needle-free auto-injection platform, the company develops and manufactures fast-acting treatments for life-threatening situations such as epilepsy, adrenal crisis, and anaphylaxis. Crossject conducts advanced regulatory development, clinical validation, and large-scale industrialization to deliver innovative therapies for global markets, with an emphasis on simplicity, reliability, and patient usability.
Publication Number
US-10799638-B2
Publication Date
2020-10-13
Expiration Date
Abstract
The present disclosure is directed towards a needleless injection device that includes a body, a gas generator, an injection system that extends axially along an injection axis and includes at least one plunger, an active ingredient reservoir, an injection nozzle that delimits at least one injection channel, a cover that houses the body of the device, a removable cap that protects a lower downstream end of the injection nozzle, a stopper that houses the cap, and a blocking element. The stopper is pivotally mounted about the injection axis between a closed position in which the stopper is locked on the injection device and an open position in which the stopper is unlocked from the injection device. The blocking element is radially interposed between the cap and the stopper, and is configured to block, by friction, the relative pivoting of the cap and of the stopper, about the injection axis.
Core Innovation
A disposable needleless injection device includes a gas generator and an injection system that extends axially along an injection axis. The injection system comprises, from upstream to downstream along an injection direction, a plunger, a reservoir containing an active ingredient, and an injection nozzle that delimits at least one injection channel. The injection system is housed under a cover, and the injection nozzle end is protected by a removable cap.
A stopper houses the removable cap and is pivotally mounted about the injection axis between a closed position, in which the stopper is locked on the injection device, and an open position, in which the stopper is unlocked from the injection device. Between the removable cap and the stopper, a blocking element is radially interposed. The blocking element is configured to block by friction the relative pivoting of the removable cap and of the stopper about the injection axis during pivotal driving of the stopper.
The stopper includes a tubular portion that delimits a housing adapted to house the removable cap and the lower downstream end of the nozzle, the tubular portion being closed at a downstream end by a removable bottom disc. The removable bottom disc includes a plurality of tightening tabs extending axially from an upper face of the removable bottom disc, each designed to bear radially on the blocking element to pinch and block pivotally the blocking element. Exemplary structures include a ring fixed on the cap crown with frictional blocking, optional elastomeric and overmolding arrangements, and locking mechanisms for the stopper and cap.
Claims Coverage
The independent claim set covers four inventive features.
Needleless injection device with axially extending injection system and gas generator
A needleless injection device including a gas generator and an injection system that extends axially along an injection axis and comprises, from upstream to downstream along an injection direction, a plunger, a reservoir containing an active ingredient, and an injection nozzle that delimits at least one injection channel.
Removable cap protected nozzle with pivoting stopper locked/unlocked about injection axis
A cover that houses the injection device and a removable cap adapted to protect a lower downstream end of the injection nozzle, together with a stopper that houses the removable cap and is pivotally mounted about the injection axis between a closed position in which the stopper is locked on the injection device and an open position in which the stopper is unlocked from the injection device.
Radially interposed friction blocking element between removable cap and stopper
A blocking element radially interposed between the removable cap and the stopper, configured to block by friction the relative pivoting of the removable cap and of the stopper about the injection axis during pivotal driving of the stopper.
Tightening tabs on removable bottom disc pinch and block pivoting of blocking element
A stopper including a tubular portion with a housing for the removable cap and the lower downstream end of the nozzle, closed at a downstream end by a removable bottom disc, where the removable bottom disc includes a plurality of tightening tabs extending axially from an upper face of the removable bottom disc and each designed to bear radially on the blocking element to pinch and block pivotally the blocking element.
The claims center on a gas-generator needleless injection device with an axially extending injection system and a nozzle protected by a removable cap, while a pivoting stopper and radially interposed blocking element prevent relative pivoting by friction. The stopper further includes a tubular portion closed by a removable bottom disc with tightening tabs that pinch and block pivoting of the blocking element.
Stated Advantages
Enables accurate/infinite angular alignment of stopper/cover in the closed state.
Blocks by friction the relative pivoting of the removable cap and of the stopper about the injection axis during pivotal driving of the stopper.
Documented Applications
Supports injection of active ingredients in a disposable needleless injection device.
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