Radial and trans-endocardial delivery catheter
Inventors
Hsueh, Wai • Palmer, Olin Jay • Comiso, Scott • Ross, James B. • Vien, Ken • Argentieri, Julio • Altman, Peter
Assignees
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Publication Number
US-10780248-B2
Publication Date
2020-09-22
Expiration Date
Abstract
A needle-injection catheter includes a catheter body having a distal end, a proximal end, a stiff proximal portion, a flexible distal portion, and a delivery lumen extending therethrough. In a first embodiment, a straight injection needle extends coaxially from a distal tip of the flexible portion of the catheter body, and a plurality of penetration limiting elements positioned circumferentially about a base of the straight injection needle and configured to fold radially inwardly against a shaft of the needle when constrained in a tubular lumen and to extend radially outwardly when unconstrained. In a second embodiment, a helical needle extends from the distal tip of the flexible portion of the catheter body. The helical needle has at least one helical delivery lumen connected to receive an injectable substance from the delivery lumen of the catheter body.
Core Innovation
The invention relates to a needle injection catheter system appropriate for transradial biotherapeutic delivery to the heart. The system includes an infusion catheter body having a distal end, a proximal end, and a delivery lumen therethrough, where the infusion catheter body has a highly flexible distal segment. A helical needle extends from the distal end of the infusion catheter body and is connected to receive an injectable substance from the catheter delivery lumen.
A fixed hockey stick guide catheter is provided that bends the helical needle and the infusion catheter body at an angle when advanced through the guide catheter. The guide catheter is fixed and has a bending rigidity greater than the bending rigidity of the distal segment, such that the guide catheter bends the helical needle and the infusion catheter body at specified angles during advancement. The guide catheter is sufficiently small to enable passage thereof through a radial artery to the heart.
To enable straight configuration advancement, a removable straightening element is insertable into the guide catheter to straighten the guide catheter. The helical needle configuration is used to deliver an injectable substance to the heart through radial access while the infusion catheter body includes a highly flexible distal segment.
Claims Coverage
The identified independent claim is clm-00001, directed to a transradial needle injection catheter system for delivery to the heart. The independent claim contains four inventive features that define a helical needle delivery system compatible with radial artery passage, including a fixed hockey stick guide catheter and a removable straightening element.
Transradial needle injection catheter with flexible distal infusion segment
A needle injection catheter system including an infusion catheter body having a highly flexible distal segment and a delivery lumen, where a helical needle extends from the distal end and is connected to receive an injectable substance from the delivery lumen.
Fixed hockey stick guide catheter for bending at defined angles
A fixed hockey stick guide catheter bent at an angle of at least 90 degrees and having a bending rigidity greater than a bending rigidity of the distal segment so that the guide catheter bends the helical needle and the infusion catheter body at an angle of at least 70 degrees when advanced through the guide catheter.
Removable straightening element for straight configuration advancement
A removable straightening element insertable into the guide catheter to straighten the guide catheter to be advanceable through vasculature in a straight configuration.
Guide catheter size enabling passage through a radial artery
A guide catheter that is sufficiently small so as to enable passage thereof through a radial artery to the heart.
Across the independent claim, the coverage centers on combining a helical needle connected to a delivery lumen with a highly flexible distal infusion segment, while using a fixed hockey-stick guide catheter with higher bending rigidity to bend the needle and infusion catheter body at specified angles during advancement through a radial artery-sized guide.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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