Methods, systems, and devices for monitoring anisocoria and asymmetry of pupillary reaction to stimulus
Inventors
Siminou, Kamran • Privitera, Claudio
Assignees
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Publication Number
US-10687702-B2
Publication Date
2020-06-23
Expiration Date
Abstract
A computer program is disclosed for performing the following method: recording images of a response of a left pupil to a stimulus thereby resulting in a first set of sequential images; recording images of a response of a right pupil to the same stimulus at the same time as the first images were recorded, thereby resulting in a second set of sequential images; displaying on a display simultaneously the first set of images and the second set of image, wherein the two sets of images are synchronized, and wherein a center of the left pupil of each image from the first set of sequential images is aligned with a center of the right pupil from the second set of sequential images on the display.
Core Innovation
The invention relates to pupillometry systems and software for assessing a health condition of a mammalian subject by recording images of a response of a left pupil to a stimulus and recording images of a response of a right pupil to the same stimulus at the same time, thereby producing first and second sets of sequential images. The two sets of images are displayed simultaneously on a pupilometer with synchronization between the sets and with aligned pupil centers on the display.
The invention further uses pupil detection to enable comparative visualization of left-right differences by identifying a center of the left pupil of each image and aligning it with a center of the right pupil on the display. The system includes a pupil finder/pupil perimeter and pupil center detection, and provides a pupil comparison program that makes left-right differences visually apparent through overlays on the displayed synchronized image sets.
In the stated approach, the pupilometer is used to detect anisocoria in the pupillary response of the subject, and anisocoria is used to diagnose the patient with an abnormal health condition. The described display overlay includes parallel lines spanning between left and right pupil perimeters, with the overlay configured to support measurement and visual differentiation between left and right pupil regions.
Claims Coverage
The independent claim set described in the provided relevant claims covers one independent method claim focused on synchronized dual-pupil imaging, aligned simultaneous display, anisocoria detection, and diagnosing an abnormal health condition when anisocoria is present. Dependent claims refine the display overlay and define how anisocoria detection is visually/quantitatively supported using distances between parallel lines in first and second sections.
Synchronized dual-pupil image recording and aligned simultaneous display
recording images of a response of a left pupil to a stimulus thereby resulting in a first set of sequential images; recording images of a response of a right pupil to the same stimulus at the same time as the first images were recorded, thereby resulting in a second set of sequential images; displaying simultaneously the first set and the second set on a display of a pupilometer, wherein the two sets are synchronized and wherein a center of the left pupil of each image from the first set is aligned with a center of the right pupil from the second set on the display
Anisocoria detection to support diagnosis
using the pupilometer to detect anisocoria in the pupillary response of the subject; diagnosing the patient with an abnormal health condition in the presence of anisocoria
Across the independent claim, the inventive core is the combination of synchronized sequential left/right pupil image acquisition to the same stimulus, simultaneous display with aligned pupil centers, and the use of detected anisocoria to diagnose an abnormal health condition.
Stated Advantages
Enables assessing a health condition of a mammalian subject by detecting anisocoria and diagnosing an abnormal health condition when anisocoria is present.
Documented Applications
Clinical use for assessing and diagnosing abnormal health conditions based on anisocoria/asymmetry of pupillary response using pupillometry.
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