Method and device for computing optical hemodynamic blood pressure
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Publication Number
US-10674921-B2
Publication Date
2020-06-09
Expiration Date
Abstract
Device for measuring blood pressure hemodynamically in blood vessels at one or more body locations comprising light source; at least three sensors including an array of at least three optical sensors, for receiving light and for obtaining a signal over time comprising temporal per pixel information for at least two wavelengths of light, and corresponding to a flow of blood within a blood vessel over time; a processing unit configured to receive the signal and generate a continuous dynamic blood pressure reading by using the temporal per pixel information for the at least two wavelengths of light to produce heart rate signals from the blood flow, and by applying a modified Windkessel model on the signal such that the blood pressure also depends on a spatial temporal pressure resistance function over time that depends on a body location of the blood flow over time, the pressure resistance function representing elastance/stiffness.
Core Innovation
A device and method measure blood pressure hemodynamically in blood vessels of a mammalian subject at one or more body locations by shining light on tissue and receiving light traversed and/or reflected from the tissue. At least three sensors, including an array of at least three optical sensors, obtain a signal over time corresponding to a flow of blood within a blood vessel, with temporal per pixel information for at least two wavelengths of light.
A processing unit supports the sensors and converts the signal to digital form when at least one sensor is analog. The processing unit generates heart rate signals from the blood flow using the temporal per pixel information for the at least two wavelengths of light, and generates a continuous dynamic blood pressure reading by applying a modified Windkessel model to the signal.
The modified Windkessel model makes the blood pressure depend on a spatial temporal pressure resistance function over time. The pressure resistance function over time depends on a body location of the blood flow over time and represents elastance, stiffness, or elastance and stiffness of the blood vessel at a given body location and at a given time. The device displays the continuous dynamic blood pressure reading on a display, and the method corresponds to the same processing and displaying.
Claims Coverage
The provided material contains two independent claims: a device claim and a method claim. Both independent claims share the same core inventive structure based on temporal per-pixel multiwavelength optical sensing of blood flow and a modified Windkessel model using a spatial-temporal pressure resistance function tied to vessel elastance and/or stiffness.
Hemodynamic blood pressure from temporal per-pixel multiwavelength optical sensing
A light source shines light at tissue, and at least three sensors including an array of at least three optical sensors receive traversed and/or reflected light and obtain a signal over time comprising temporal per pixel information for at least two wavelengths, the signal corresponding to a flow of blood within a blood vessel over time.
Continuous dynamic blood pressure using heart-rate signals and a modified Windkessel model
Hardware and software support the sensors and convert the signal to digital form when at least one sensor is analog; a processing unit receives the signal and generates a continuous dynamic blood pressure reading by using the temporal per pixel information for the at least two wavelengths to produce heart rate signals from the blood flow, and by applying a modified Windkessel model on the signal.
Spatial temporal pressure resistance function representing elastance and/or stiffness
The modified Windkessel model makes the blood pressure depend on a spatial temporal pressure resistance function over time, wherein the pressure resistance function over time depends on a body location of the blood flow over time and represents elastance, stiffness or elastance and stiffness of the blood vessel at a given body location and at a given time.
Display of continuous dynamic blood pressure reading
A display configured to display the continuous dynamic blood pressure reading.
Across the device and method claims, the inventive features center on multiwavelength temporal per-pixel optical sensing to derive heart rate signals from blood flow and to feed a modified Windkessel model whose pressure resistance is expressed as a spatial-temporal function representing elastance and/or stiffness at a given body location and time.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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