Head modeling for a therapeutic or diagnostic procedure
Inventors
Mainkar, Neeraj • Pillutla, Ravi • Ghiron, Kenneth Marc • Riehl, Mark Edward
Assignees
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Publication Number
US-10636520-B2
Publication Date
2020-04-28
Expiration Date
Abstract
A model of a human subject's head may be generated to assist in a therapeutic and/or diagnostic procedure. A treatment and/or diagnostic system may generate a fitted head model using a predetermined head model and a plurality of points. The plurality of points may include facial feature information and may be determined using a sensor, for example, an IR or optical sensor. One or more anatomical landmarks may be determined and registered in association with the fitted head model using the facial feature information, for example, without the use of additional image information, such as an MRI image. The fitted head model may include visual aids, for example, anatomical landmarks, reference points, marking of the human subject's MT location, and/or marking of the human subject's treatment location. The visual aids may assist a technician to perform the therapeutic and/or diagnostic procedure of the human subject.
Core Innovation
The invention determines a plurality of points associated with a human subject’s head using a sensor and without requiring magnetic resonance imaging (MRI) image information, x-ray image information, or computer tomography (CT) image information. A subset of the plurality of points comprises facial feature information, and the system or method uses these points to create a digital three-dimensional reconstruction of the head and generate a fitted head model using a predetermined head model and the plurality of points.
Using the facial feature information, the invention determines a location of one or more anatomical landmarks on the fitted head model. The anatomical landmarks comprise one or more of a nasion, an inion, a lateral canthus, an external auditory meatus, or one or more preauricular points of the human subject, and the landmark results are used to determine a position of the treatment coil or determine a treatment location or a reference point used to determine the treatment location.
The invention performs transcranial magnetic stimulation (TMS) at the treatment location using the treatment coil. The fitted head model may incorporate an electroencephalogram (EEG) 10–20 coordinate grid, and one or more predetermined or fitted head models may contain no information relating to the human subject’s hair, with point subsets used for generating the fitted head model optionally excluding points associated with the human subject’s hair.
Claims Coverage
The document includes three independent claims that collectively cover a system and methods for creating a digital three-dimensional reconstruction of a human head and for determining a TMS treatment location. Across the independent claims, the main inventive features are sensor-based acquisition of head points without MRI/x-ray/CT image information, fitting of a predetermined head model, landmark localization from facial feature information, and use of the landmark results to determine a treatment location or treatment coil position for performing TMS.
Sensor-determined points without MRI/x-ray/CT image information
Determine a plurality of points associated with the human subject’s head using the sensor and without requiring the use of MRI image information, x-ray image information, or CT image information, wherein a subset of the plurality of points comprise facial feature information.
Fitted head model from a predetermined head model and points
Generate a fitted head model using a predetermined head model and the plurality of points.
Anatomical landmark location on the fitted head model using facial feature information
Determine a location of one or more anatomical landmarks on the fitted head model using the facial feature information, the anatomical landmarks comprising one or more of a nasion, an inion, a lateral canthus, an external auditory meatus, or one or more preauricular points.
Treatment coil positioning or treatment location determination based on the landmarks
Determine a position of the treatment coil or determine a treatment location or a reference point used to determine the treatment location on the fitted head model based on the one or more anatomical landmarks, and perform TMS at the treatment location.
Sensor point determination using TMS coil movement around the head
Determine a plurality of points associated with the human subject’s head using a sensor by moving a TMS coil around the human subject’s head, then generate a fitted head model, determine anatomical landmarks using the facial feature information, determine a treatment location or reference point without requiring MRI/x-ray/CT image information, and perform TMS at the treatment location.
Across the independent claims, coverage centers on sensor-based determination of facial-feature-including head points without MRI/x-ray/CT image information, fitting a head model from a predetermined head model, determining anatomical landmarks from facial feature information, and using those landmark results to determine a treatment location or treatment coil position for performing TMS.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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