Devices and methods for the treatment of heart failure
Inventors
Assignees
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Publication Number
US-10624621-B2
Publication Date
2020-04-21
Expiration Date
Abstract
A device (10) for treating heart failure in a patient. The device (10) comprising a body (12), at least one passage (18) through the body (12), at least one one way valve (20) in the passage (18) and a mounting means (14) adapted for mounting the body (12) in an opening provided in the patient's atrial septum. In use, the device (10) is oriented such that, when the patient's left atrial pressure exceeds the patient's right atrial pressure by a predetermined amount, the one way valve(s) (20) opens to allow blood flow through the passage(s) from the left atrium to the right atrium to thereby reduce the left atrial pressure.
Core Innovation
The invention provides a device for treating a heart condition in a patient by implanting a catheter-deliverable body across an atrial septum opening using first and second flanges. The body includes an inner lumen defining at least one passageway, and the body has a collapsed configuration with a reduced diameter for passing through a catheter and an expanded configuration with a larger diameter.
In the expanded configuration, the first and second flanges are adapted for mounting the body in an opening in the patient's atrial septum with a first exterior face contacting the atrial septum and a second exterior face facing away from the atrial septum. The at least one valve is disposed inside the passageway and is positioned closer to a central portion of the passageway than the ends along a longitudinal axis.
The valve is adapted to open and allow blood flow through the passageway from the left atrium to the right atrium. The valve arrangement is adapted to reduce the left atrial pressure when the patient's left atrial pressure exceeds the patient's right atrial pressure by a predetermined amount, while preventing flow from the right atrium to the left atrium when the right atrial pressure exceeds the left atrial pressure.
Claims Coverage
The document provides one independent claim directed to a catheter-deliverable atrial-septum device with a one-way valve based on a pressure differential threshold. The claim set also includes dependent claims that refine structural and functional aspects, including valve types and pressure differential thresholds.
Catheter-deliverable collapsible/expandable atrial septum-mounted body with passageway
A body having an inner lumen defining at least one passageway with a first end and a second end, wherein the body has a collapsed configuration with a reduced diameter for passing through a catheter and an expanded configuration with a larger diameter.
First and second flanges configured for mounting across an atrial septum opening
A first flange and a second flange positioned on either end of the body, with an expanded flange configuration that mounts the body in an opening in the patient's atrial septum with a first exterior face contacting the atrial septum and a second exterior face facing away from the atrial septum.
One-way valve disposed inside the passageway for left-to-right flow
At least one valve disposed inside the passageway, positioned closer to a central portion of the passageway than the first or second ends along a longitudinal axis of the passageway, wherein the valve is adapted to open and allow blood flow through the passageway from the left atrium to the right atrium.
Pressure-differential threshold for opening and reverse-flow prevention
The valve is adapted to reduce the left atrial pressure when the patient's left atrial pressure exceeds the patient's right atrial pressure by a predetermined amount and prevent flow from the right atrium to the left atrium when the right atrial pressure exceeds the left atrial pressure.
Across the independent claim, the core inventive coverage is a collapsible/expandable catheter-deliverable body mounted across an atrial septum opening by first and second flanges, with a centrally positioned valve that opens for left-to-right blood flow when left atrial pressure exceeds right atrial pressure by a predetermined amount and that prevents reverse flow.
Stated Advantages
Reduce the left atrial pressure when the patient's left atrial pressure exceeds the patient's right atrial pressure by a predetermined amount.
Prevent flow from the right atrium to the left atrium when the right atrial pressure exceeds the left atrial pressure.
Documented Applications
Treating a heart condition in a patient, including left atrial hypertension/diastolic or systolic dysfunction, by implanting a valve-enabled device across an atrial septum opening.
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