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Publication Number
US-10617722-B2
Publication Date
2020-04-14
Expiration Date
Abstract
Honey-cannabinoid therapeutic compositions and methods. A therapeutic composition providing therapeutic effects to at least some patients is described including honey; at least one cannabinoid; and optionally, at least two non-cannabinoid cannabis compounds, hydrogen peroxide, at least one food-approved antioxidant, glucose oxidase, and/or catalase, and water; where the composition is homogeneous; has oxidative power low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month; contains hydrogen peroxide at a concentration low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month; contains at least one food-approved antioxidant at a concentration low enough to keep THC oxidation at a rate of less than 20% per month; contains glucose oxidase at a concentration low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month; and/or contains catalase at a concentration high enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month.
Core Innovation
The invention relates to a honey-cannabinoid therapeutic composition providing therapeutic effects to at least some patients. The composition includes honey and at least one cannabinoid, and optionally includes at least two non-cannabinoid cannabis compounds and/or oxidative-stability components selected from hydrogen peroxide, at least one food-approved antioxidant, glucose oxidase, and catalase.
The composition is formulated as a mixture with water at a concentration of less than 26% by weight and is characterized by being homogeneous. It is further characterized by oxidative power and/or by containing one or more of hydrogen peroxide, food-approved antioxidant, glucose oxidase, and catalase in defined relative ways such that tetrahydrocannabinol oxidation is kept at a rate of less than 20% per month.
The invention additionally covers embodiments that refine cannabinoid content and mixture characteristics, including a cannabinoid mixture having cannabidiol and tetrahydrocannabinol in a weight ratio of cannabidiol to tetrahydrocannabinol greater than 5. Other embodiments narrow cannabinoid concentration and specify categories of non-cannabinoid cannabis compounds. The document also describes product forms including a digestible product and a topical application product using the claimed therapeutic composition.
Claims Coverage
The document provides one independent claim covering a therapeutic honey-cannabinoid composition with multiple optional stability-related additives, constrained by aqueous concentration and by one or more defined oxidative-stability characteristics. Dependent claims add further limitations on cannabinoid concentration, cannabinoid mixture ratios, the types of non-cannabinoid cannabis compounds, additional required characterization features, and specific delivery forms.
Homogeneous honey-cannabinoid therapeutic composition in water below 26% by weight
A therapeutic composition comprising honey; at least one cannabinoid; optionally at least two non-cannabinoid cannabis compounds selected from hydrogen peroxide, food-approved antioxidant, glucose oxidase, and/or catalase; and water at a concentration of less than 26% by weight, wherein the composition is characterized by being homogeneous and further characterized by oxidative-stability features.
Oxidative power low enough to keep THC oxidation below 20% per month
A therapeutic composition in which the composition is characterized by having oxidative power low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month.
Hydrogen peroxide and antioxidants at concentrations that keep THC oxidation below 20% per month
A therapeutic composition characterized by containing hydrogen peroxide at a concentration low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month and/or containing at least one food-approved antioxidant at a concentration low enough to keep THC oxidation at a rate of less than 20% per month.
Enzyme-based oxidative control to keep THC oxidation below 20% per month
A therapeutic composition characterized by containing glucose oxidase at a concentration low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month and/or containing catalase at a concentration high enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month.
Additional required characterization features selected from oxidative stability options
A therapeutic composition wherein the composition is further characterized by containing at least two additional features selected from being homogeneous; having oxidative power low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month; containing hydrogen peroxide at a concentration low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month; containing at least one food-approved antioxidant at a concentration low enough to keep THC oxidation at a rate of less than 20% per month; containing glucose oxidase at a concentration low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month; and/or containing catalase at a concentration high enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month.
CBD:THC weight ratio greater than 5
A therapeutic composition characterized by a cannabinoid mixture comprising cannabidiol and tetrahydrocannabinol in a weight ratio of cannabidiol to tetrahydrocannabinol greater than 5.
Cannabinoid concentration less than 10% by weight
A therapeutic composition having a cannabinoid concentration of less than 10% by weight.
Non-cannabinoid cannabis compounds selected from terpenes, terpenoids, and flavonoids
A therapeutic composition containing at least two non-cannabinoid cannabis compounds, with at least one selected from terpenes, terpenoids, and flavonoids.
Digestible product containing the therapeutic composition
A digestible product comprising the therapeutic composition of claim 1.
Overall, the claim set centers on a honey-cannabinoid therapeutic composition with water at less than 26% by weight, characterized as homogeneous and stabilized against tetrahydrocannabinol oxidation to less than 20% per month using one or more oxidative-stability features. Dependent claims further specify CBD:THC ratio, cannabinoid concentration, categories of non-cannabinoid cannabis compounds, additional required characterization features, and a digestible product embodiment.
Stated Advantages
Keeps tetrahydrocannabinol oxidation at a rate of less than 20% per month.
Provides therapeutic effects to at least some patients.
Documented Applications
A digestible product containing the therapeutic composition.
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