Heart mapping system
Inventors
Smaill, Bruce • Zhao, Jichao • Servent, Judit Chamorro • Meng, Shu
Assignees
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Publication Number
US-10610112-B2
Publication Date
2020-04-07
Expiration Date
Abstract
A method of determining physiological information for an internal body surface using an open catheter comprising multiple sensors. Sensor potentials are obtained and used to determine catheter potentials within the catheter, and the physiological information for the internal body surface is determined using at least some of the catheter potentials.
Core Innovation
The invention relates to a heart electro-anatomic mapping system that determines physiological information for an internal body surface using an open catheter comprising multiple electrodes. The catheter is open and blood-permeable, and the electrodes lie on a closed virtual 3D surface that bounds a volume within the catheter. Measured electrode potentials are interpolated over the closed virtual 3D surface, and the resulting information is used to estimate an internal potential field in the catheter volume.
A forward solution based on boundary conditions derived from the measured electrode potentials provides a set of electric potentials within the volume. The computed potentials are then used to determine additional boundary information, such as potential gradients and flux, for a subsequent inverse solution. The inverse problem reconstructs electrical potentials on an endocardial surface as physiological information.
The document compares boundary element method and meshless methods, including MFS-based methods, for performing the inverse mapping, and describes a computational proof-of-concept with correlation and a noise-robust global mapping approach. It further outlines real-time processing in which catheter and geometry acquisition is followed by iterative forward and inverse mapping over time and visualization, including global-to-region-of-interest catheter repositioning.
Claims Coverage
Two independent claims define a method and a system for determining physiological information on an internal body surface using an open catheter with multiple electrodes. Across the independent claims, the coverage centers on an iterative workflow that derives boundary conditions, performs a forward differential-equation solution to compute potentials, and then performs an inverse differential-equation solution to determine physiological information, using the same key functional steps.
Iterative boundary-condition-driven forward and inverse solutions
Obtaining a first set of electric potentials using a plurality of electrodes; determining a first set of boundary conditions from the first set of electric potentials; using the first set of boundary conditions to perform a forward solution to a first set of differential equations to provide a second set of electric potentials within the volume; determining a second set of boundary conditions from the second set of electric potentials; using the second set of boundary conditions to perform an inverse solution to a second set of differential equations; and determining the physiological information for the internal body surface using the inverse solution.
Open catheter with multiple electrodes bounding a volume
An open catheter comprising multiple electrodes bounding a volume within the catheter, where the electrodes are used to obtain the first set of electric potentials that enable derivation of boundary conditions for the forward and inverse solutions.
The independent claims collectively cover both a method and a system implementing an iterative boundary-condition-driven forward and inverse solution workflow using an open catheter with multiple electrodes bounding a volume, to determine physiological information for an internal body surface.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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