Insert for catheter system
Inventors
Assignees
ATTWILL MEDICAL SOLUTIONS STERILFLOW LP • ATTWILL MEDICAL SOLUTIONS STERIFLOW LP
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Publication Number
US-10525192-B2
Publication Date
2020-01-07
Expiration Date
Abstract
An insert for a catheter system can include an insert housing which defines a portion of a fluid pathway of the catheter system, a cartridge positioned within the insert housing in a manner to allow fluid flow along the fluid pathway such that fluid contacts the insert during the fluid flow, and an active agent associated with the cartridge. The active agent and the cartridge can be adapted to release active agent from the cartridge during the fluid flow.
Core Innovation
An insert for a catheter system is provided, where an insert housing defines a portion of a fluid pathway of the catheter system. A cartridge is positioned within the insert housing so that fluid flow along the fluid pathway contacts the cartridge, and an active agent is associated with the cartridge such that the active agent and the cartridge are adapted to release during the fluid flow through the insert.
The active agent is adapted to release at least 80 wt % of the active agent from the cartridge during the fluid flow of a locking fluid. The active agent comprises at least one of chlorhexidine gluconate, chlorhexidine digluconate, silver sulfadiazine, rifampicin, minocycline, or chlorhexidine diacetate.
Release is described as being tunable by cartridge properties, including porosity, channels, holes, and coatings, and by processing such as lyophilization and chemical modification. Multiple cartridge and integration configurations are described for coupling the insert with catheter-system components, including luer-type inserts and syringe/connector arrangements, valve/stopcock interfacing, and non-luer mechanical dosing features.
Claims Coverage
The claim set coverage centers on one independent claim, which defines an insert for a catheter system including an insert housing, a cartridge in a fluid pathway, and an active agent adapted for a specified high-percentage release during catheter locking-fluid flow. The remaining dependent claims refine structural configurations and add quantitative and categorical limitations relating to release timing and active-agent selection.
Insert housing defining a fluid pathway portion with a cartridge contacted by locking-fluid flow
An insert for a catheter system comprising an insert housing defining a portion of a fluid pathway, a cartridge positioned within the insert housing such that fluid flows along the fluid pathway and contacts the cartridge during fluid flow, and an active agent associated with the cartridge.
Active agent releasing at least 80 wt % during locking-fluid flow
The active agent and the cartridge are adapted to release at least 80 wt % of the active agent from the cartridge during the fluid flow of a locking fluid.
Active agent selected from specified chlorhexidine forms and other antimicrobial agents
The active agent comprises at least one of chlorhexidine gluconate, chlorhexidine digluconate, silver sulfadiazine, rifampicin, minocycline, or chlorhexidine diacetate.
Overall, the independent claim requires an insert-housing fluid pathway with a cartridge that is contacted by locking-fluid flow and an active agent adapted to release at least 80 wt % during that flow, where the active agent is limited to specified chlorhexidine forms and other listed antimicrobial agents.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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