Method for manufacturing microneedle
Inventors
Kim, Jung Dong • Jeong, Do Hyeon • Kim, Beom Joon • Kim, Hong Kee
Assignees
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Publication Number
US-10507312-B2
Publication Date
2019-12-17
Expiration Date
Abstract
The present disclosure relates to a method for manufacturing a microneedle enabling product quality and efficiency in production to be improved by reducing the time needed for spotting a viscous material. The method for manufacturing a microneedle, according to the present disclosure, comprises the steps of spotting a viscous material on a plurality of spots on a film by supplying the viscous material to the upper surface of the film by means of a plurality of through-holes provided on an injection plate, elongating the viscous material spotted on the film; and coagulating the elongated viscous material.
Core Innovation
The invention relates to a method of manufacturing a microneedle. A film is disposed on a stage, and the stage includes a plurality of filling grooves formed concavely on an upper surface. An injection plate is adhered to an upper surface of the film so that through holes of the injection plate align with the plurality of filling grooves.
The method includes spotting a viscous material on a plurality of points on the film by supplying the viscous material on the upper surface of the film through the through holes. After spotting, the viscous material spotted on the film is elongated, and the elongated viscous material is coagulated to form the microneedle.
The injection plate is surface treated to lower an adhesive force between the injection plate and the viscous material. The disclosed approach reduces viscous-material spotting time and improves product quality by controlling spotted volume and preventing leakage or staining, thereby reducing defects caused by evaporation and viscosity deviation.
Claims Coverage
The independent claim contains three inventive features comprising the stage-film filling-groove arrangement, the adhered injection plate aligned to through holes, and the spotting, elongating, and coagulating sequence, together with a surface-treatment limitation to lower adhesive force.
Filling-groove stage with adhered film
A film is disposed on a stage having a plurality of filling grooves formed concavely on an upper surface, and an injection plate is adhered to an upper surface of the film so that through holes of the injection plate align with the plurality of filling grooves.
Through-hole spotting followed by elongating and coagulating
Viscous material is supplied through the through holes onto the upper surface of the film to spot a plurality of points, then the spotted viscous material is elongated and coagulated to form the microneedle.
Lower adhesive force injection plate via surface treatment
The injection plate is surface treated to lower an adhesive force between the injection plate and the viscous material.
The independent claim defines microneedle manufacturing by concave filling grooves in the stage, an adhered injection plate aligned with the filling grooves to supply viscous material through through holes onto the film, followed by elongating and coagulating, with surface treatment of the injection plate to lower adhesive force to the viscous material.
Stated Advantages
Reduced viscous-material spotting time.
Improved product quality by controlling spotted volume and preventing leakage or staining.
Reduced defects caused by evaporation and viscosity deviation.
More uniform microneedle dimensions associated with improved skin penetration and pain.
Documented Applications
Manufacturing microneedles using a film on a stage with concave filling grooves, with viscous-material spotting through an injection plate having through holes, followed by elongating and coagulating.
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