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Assignees
FreMon ScientificFreMon Scientific develops biomedical platforms focused on dry, electronically controlled thawing of blood, plasma, and cell therapy products. Its core solutions include portable thawing devices and disposable thermal sleeves for optimized, contamination-reduced, and traceable thawing workflows. The systems are validated for regulatory compliance, supported by clinical studies, and utilized in hospitals, laboratories, and production settings globally.
FreMon Scientific develops biomedical platforms focused on dry, electronically controlled thawing of blood, plasma, and cell therapy products. Its core solutions include portable thawing devices and disposable thermal sleeves for optimized, contamination-reduced, and traceable thawing workflows. The systems are validated for regulatory compliance, supported by clinical studies, and utilized in hospitals, laboratories, and production settings globally.
Abstract
Dry thawing systems and devices for thawing biological substances are provided herein. Methods for thawing biological substances are also provided.
Core Innovation
A dry thawing system includes a housing having a cavity configured to receive an enclosed biological substance. A first heating assembly disposed within the housing is in thermal communication with an enclosed biological substance received within the cavity, and includes a heater and a heating cushion in thermal communication with the heater. The heating cushion comprises a material having good thermal conductivity and is positioned between the heater and the enclosed biological substance when received within the cavity.
The system includes at least one temperature sensor disposed within the housing and configured to measure a temperature of at least one of the heater and the heating cushion. In one configuration, a temperature sensor is configured to regulate power to the heater based on the measured temperature, with power delivered by a power supply. The system further includes a chamber door pivotally mounted to the housing, and a sensor disposed on the chamber door configured to detect the presence of an authentication tag coupled to an enclosed biological substance received within the cavity.
In configurations with enhanced control, the dry thawing system includes controller functionality in communication with the temperature sensor, where the controller communicates temperature to a processor. In failsafe configurations, the system transmits a failsafe signal to a power supply when measured temperatures exceed predetermined threshold temperatures, and receipt of the failsafe signal terminates delivery of power to the heater.
Claims Coverage
Two independent claims are present. They cover a dry thawing system with a thermally conductive heating cushion and in-housing temperature measurement plus chamber-door authentication-tag detection, and a dry thawing system with temperature detection of the enclosed biological substance plus controller/processor communication plus chamber-door authentication-tag detection.
Thermally conductive heating cushion between heater and enclosed biological substance with in-housing temperature sensing and chamber-door authentication-tag detection
A dry thawing system comprising a housing cavity for an enclosed biological substance, a first heating assembly with a heater and a heating cushion in thermal communication, where the heating cushion comprises a material having good thermal conductivity and is positioned between the heater and the enclosed biological substance, at least one temperature sensor disposed within the housing configured to measure a temperature of at least one of the heater and the heating cushion, and a sensor disposed on a chamber door pivotally mounted to the housing configured to detect the presence of an authentication tag coupled to the enclosed biological substance.
Dry thawing from frozen state to fluid state with enclosed-substance temperature sensing, controller/processor communication, and chamber-door authentication-tag detection
A dry thawing system comprising a housing cavity for an enclosed biological substance, a first heating assembly with a heater configured to selectively generate thermal energy to heat an enclosed biological substance from a frozen state to a fluid state, a temperature sensor configured to detect a temperature of the enclosed biological substance received within the cavity, a controller in communication with the temperature sensor configured to communicate the temperature to a processor, and a sensor disposed on a chamber door pivotally mounted to the housing configured to detect the presence of an authentication tag coupled to the enclosed biological substance.
Across the independent claims, the main inventive coverage combines a heating arrangement that thermally communicates with an enclosed biological substance, temperature sensing of the heater, heating cushion, or enclosed biological substance, controller/processor communication in at least one configuration, and chamber-door detection of an authentication tag coupled to the enclosed biological substance.
Stated Advantages
Documented Applications
No documented applications found
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