Blood pressure reduction with dietary supplements
Inventors
Sparks, William S. • De Luca, Daryl L. • De Luca, Denis R. • Houston, Mark
Assignees
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Publication Number
US-10391139-B2
Publication Date
2019-08-27
Expiration Date
Abstract
Blood Pressure Reduction with Dietary Supplements Abstract A daily dose of 6,000 mg of taurine, 1,000 mg of vitamin C, 150 mg of grape seed extract, 100 mg of vitamin B6, 2 mg of biotin, 2,000 IU of vitamin D3, and 87 mg of magnesium is shown to reduce blood pressure in hypertensive individuals by more than 10 mm Hg.
Core Innovation
The invention is directed to orally ingested dietary supplement compositions for treating high blood pressure in a human in need thereof, including hypertension and pre-hypertension. The compositions include therapeutically effective amounts of taurine and vitamin C as major constituents, and further include additional nutritional components and grape seed extract in multi-ingredient variants. The compositions are formulated for oral ingestion.
The dietary supplement compositions further include grape seed extract, vitamin B6, biotin, vitamin D3, and optionally magnesium, with magnesium identified as magnesium ascorbate in the described formulations. The approach is based on administering a daily dose of the composition for a period described as approximately 6 weeks, and evaluating blood pressure outcomes.
In the described randomized/blinded study example, treatment with the disclosed daily dose is reported to reduce systolic and diastolic blood pressure by at least 10 mm Hg in hypertensive individuals over approximately 6 weeks. The outcomes are illustrated by FIGs. 1-2, with systolic and diastolic endpoints used to assess the claimed therapeutic effect.
Claims Coverage
The provided independent claim covers one dietary supplement composition for treating high blood pressure in a human in need thereof, formulated for oral ingestion and restricted to an essentially defined set of ingredients. One independent claim is present in the provided claim set.
Orally ingested dietary supplement composition consisting essentially of specified ingredients
A dietary supplement composition for treating high blood pressure in a human in need thereof, formulated for oral ingestion and consisting essentially of therapeutically effective amounts of vitamin C, biotin, grapeseed extract, vitamin D3, vitamin B6, taurine, and magnesium ascorbate.
The independent claim is directed to an oral dietary supplement for high blood pressure that consists essentially of therapeutically effective amounts of the specifically listed nutrients and extract, including taurine and vitamin C, plus biotin, grapeseed extract, vitamin D3, vitamin B6, and magnesium ascorbate.
Stated Advantages
Reduces systolic blood pressure by at least 10 mm Hg in hypertensive individuals compared to placebo over approximately 6 weeks.
Reduces diastolic blood pressure by at least 10 mm Hg in hypertensive individuals compared to placebo over approximately 6 weeks.
Documented Applications
Treating high blood pressure in a human in need thereof, including hypertension and pre-hypertension, using orally ingested dietary supplement compositions based on the disclosed ingredient set.
Use in a randomized/blinded study example assessing systolic and diastolic blood pressure outcomes with comparison to placebo.
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