Patient care recommendation system

Inventors

Batchinsky, AndriyCancio, Leopoldo C.Salinas, Jose

Assignees

United States Department of the ArmyUS Army Medical Research and Development Command

Publication Number

US-10383526-B2

Publication Date

2019-08-20

Expiration Date

2031-08-05

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Abstract

Disclosed are systems and methods to provide a patient care recommendation. The systems and methods receive patient information and a plurality of patient physiological signals that are related to a patient. The systems and methods are then operable to produce at least one derived patient signal from at least one of the plurality of patient physiological signals. The systems and methods use the patient information, at least one of the plurality of patient physiological signals, and the at least one derived patient signal to provide at least one patient care recommendation.

Core Innovation

The invention relates to systems and methods for providing patient care recommendations, particularly for quickly and accurately recommending life saving interventions (LSIs) for patients in critical condition. The system receives patient information and multiple patient physiological signals, derives signals from these physiological signals, and uses this data collectively to formulate patient care recommendations.

The problem addressed stems from inadequacies in current patient triage and diagnosis processes, where limited physiological data such as heart rate, blood pressure, respiratory rate, and oxygen saturation are typically used. These conventional measurements often fail to capture the true patient condition due to human compensatory mechanisms, leading to possible incorrect or delayed treatment decisions. This is especially problematic when prioritizing care among multiple patients in time-sensitive environments.

Accordingly, the invention provides a system and method capable of acquiring a plurality of physiological signals from a patient, generating derived patient signals through statistical and nonlinear analysis, and applying patient information alongside these signals to produce recommendations. This approach aims to overcome the limitations of current practices by incorporating a more comprehensive and dynamic set of data to inform patient care.

Claims Coverage

The patent includes three types of independent claims: a system claim, a computer-readable medium claim, and a method claim. Each claim focuses on determining a patient health indicator based on the degree of decoupling between respiratory and heart signals.

Patient health determination based on respiratory-heart signal decoupling

A system comprising respiration and heart monitoring devices providing respective signals to a diagnosis engine programmed to receive these signals, determine a degree of decoupling using a ratio of R-to-R intervals within inspiration and expiration cycles from an electrocardiography waveform, and provide a patient health indicator based only on this degree of decoupling which indicates a need for life saving intervention.

High-precision real-time signal acquisition

The system and method receive each respiratory and heart signal with a granularity of at most 5 microseconds, ensuring high temporal resolution of incoming patient physiological data.

Relative decoupling assessment against healthy baseline

The determined degree of decoupling is assessed relative to a coupling observed in healthy patients, providing context for evaluating patient health status.

Association of decoupling with physiological instability

The degree of decoupling is linked to physiological signs of instability stored in a database coupled with the diagnosis engine, enabling informed assessments and recommendations.

Calculation-based determination of decoupling

The diagnosis engine performs calculations on subsets of respiratory and heart signals to derive the degree of decoupling, operationalizing the measurement of interaction between these physiological systems.

Display of patient health indicator

The system includes a display coupled to the diagnosis engine to visually present the patient health indicator derived from the decoupling analysis.

The independent claims cover a system, a computer-readable medium, and a method all directed to determining a patient health indicator based solely on a calculated degree of decoupling between respiratory and heart signals at high temporal resolution, relating this decoupling to healthy baselines and physiological instability, and providing the health indicator visually to medical personnel.

Stated Advantages

Enables quick and accurate provision of life saving intervention recommendations for patients in critical condition.

Overcomes limitations of conventional physiological monitoring by incorporating derived patient signals from nonlinear and statistical analyses.

Supports monitoring and decision-making for multiple patients by providing comprehensive patient data interpretation.

Non-invasive assessment of patient health through analysis of cardiorespiratory coupling, providing early indicators of deterioration.

Documented Applications

Use in hospital or patient care facilities including emergency rooms, intensive care units, operating rooms, and step down units.

Deployment in en-route care vehicles such as helicopters and ground ambulances for patient transport.

Application in battlefield situations or mass casualty events to assist medics in prioritizing care and interventions.

Remote monitoring of individual patients via wearable monitoring systems transmitting physiological data to remote diagnosis engines.

Management of multiple patients in large hospitals or battlefield contexts through remote patient monitoring systems providing care recommendations.

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