System and method for generating electromagnetic treatment protocols for the nervous system
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Publication Number
US-10322295-B2
Publication Date
2019-06-18
Expiration Date
Abstract
A system includes a communication interface for receiving information that includes data collected from an array of neural activity sensors that were placed on a patient during a session of applied stimuli. A processor is configured to analyze the received information to obtain a frequency spectrum for each sensor for a given stimulus of the applied stimuli. Neural network frequencies that correspond to an indicated impaired functionality of the nervous system of the patient are selected. For each selected frequencies, a spatial map of neural activity is generated. Each of the generated spatial maps is compared with retrieved corresponding spatial maps to identify treatment frequencies from among the selected neural network frequencies. A treatment protocol is generated for input into an electromagnetic field generator to cause the generator to apply to the patient an electromagnetic field at each identified treatment frequency.
Core Innovation
The invention automatically generates a treatment protocol for applying therapeutic electromagnetic fields to treat impaired functionality of a nervous system of a patient. It receives information that includes data collected from an array of neural activity sensors placed on the patient during a session of applied stimuli, and the received information is analyzed to obtain a frequency spectrum for each sensor for a given stimulus of the applied stimuli.
Neural network frequencies are then selected that have been previously associated with a neural network of components of a nervous system associated with impaired functionality, where the association is indicated by clinical data regarding the patient. For each selected neural network frequency, the system generates a spatial map of neural activity for the array of sensors and compares the generated spatial maps with retrieved spatial maps that correspond to the neural network frequency to identify treatment frequencies among the selected neural network frequencies.
Using the identified treatment frequencies, the invention generates a treatment protocol for input into an electromagnetic field generator to cause the generator to apply to at least an entire head of the patient an electromagnetic field at each treatment frequency. The protocol generation is based on sensor frequency spectra, spatial neural activity maps, and comparison to retrieved spatial maps or profiles corresponding to neural network frequencies associated with the patient’s impaired functionality.
Claims Coverage
The independent claim set covers a protocol-generation system and a method that select treatment frequencies from neural activity sensor data and generate a treatment protocol for an electromagnetic field generator. The inventive features comprise per-sensor frequency spectrum analysis, selection of neural network frequencies linked to impaired functionality indicated by clinical data, spatial mapping and comparison to retrieved spatial maps to identify treatment frequencies, and protocol generation for applying therapeutic electromagnetic fields to at least an entire head of the patient.
Per-sensor frequency spectrum analysis from sensor array during applied stimuli
Analyzing the received information to obtain a frequency spectrum for each sensor of said array of sensors for a given stimulus of the applied stimuli.
Selecting neural network frequencies associated with impaired functionality indicated by clinical data
Selecting one or a plurality of neural network frequencies that have been previously associated with a neural network of components of a nervous system that is associated with an impaired functionality of the nervous system of the patient that is indicated by clinical data regarding the patient.
Generating spatial neural activity maps for selected neural network frequencies
For each neural network frequency of the selected one or a plurality of neural network frequencies, generating a spatial map of neural activity for the array of sensors.
Comparing generated spatial maps with retrieved spatial maps to identify treatment frequencies
Comparing each of the generated spatial maps with one or a plurality of retrieved spatial maps that correspond to that neural network frequency to identify one or a plurality of treatment frequencies from among said one or a plurality of neural network frequencies.
Generating a treatment protocol for electromagnetic field generator applying to at least an entire head
Generating a treatment protocol for input into an electromagnetic field generator to cause the generator to apply to at least an entire head of the patient an electromagnetic field at each treatment frequency of said one or a plurality of treatment frequencies.
Electrically conductive coil driven by treatment protocol
A generator that is configured to generate an electrical current to flow through the coil in accordance with an input treatment protocol.
Fourier transform or wavelet transform for frequency spectrum analysis
Analyzing the received information to obtain a frequency spectrum includes applying a Fourier transform or wavelet transform to the collected data.
The independent claims collectively cover automated generation of treatment protocols by extracting per-sensor frequency spectra from neural activity sensor data during applied stimuli, selecting neural network frequencies associated with impaired functionality indicated by clinical data, generating and comparing spatial neural activity maps to retrieved spatial maps to identify treatment frequencies, and producing a treatment protocol for an electromagnetic field generator to apply an electromagnetic field to at least an entire head at the identified treatment frequencies.
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