Blister advancement mechanism comprising an actuator plate
Inventors
Toksoz, Zafer • Cifter, Umit • Turkyilmaz, Ali • Mutlu, Onur
Assignees
Sanovel Ilac Sanayi ve Ticaret AS • Arven Ilac Sanayi ve Ticaret AS
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Publication Number
US-10207067-B2
Publication Date
2019-02-19
Expiration Date
Abstract
The present invention relates to improvements made in the blister advancement mechanism of dry powder inhaler devices. A dry powder inhaler device mechanism comprising an actuator plate and a transmission wheel is provided.
Core Innovation
The invention relates to an improved dry powder inhaler device having a blister advancement mechanism. A trigger moves in an axial/linear direction in the body, and the axial/linear motion is converted into rotational motion for driving a main drum. The main drum advances a blister strip having drug-carrying cavities for drug administration.
An actuator plate is provided with a socket sized to receive a transmission wheel. A series of teeth aligned in the socket on the axial/linear direction in which the trigger is moved meshes with the transmission wheel to transfer rotational motion to the main drum. The transmission wheel is disposed on and substantially coaxially with the main drum so that the transmission wheel meshes with the teeth aligned in the socket.
The described mechanism further includes a trigger having a compressed helical pretension spring and a transmission wheel configuration that produces rotational drive behavior while the lid closes and resets the mechanism. The blister strip wound about the main drum includes a protective layer or cover wound around a gear set and a main layer wound around additional gears, enabling administration of the drug in the next cavity of the blister strip. The arrangement also includes actuator-plate body barriers that limit actuator-plate displacement and structural features such as tooth/toothless edges and a toothless surface section.
Claims Coverage
Independent claim clm-00001 sets out the core dry powder inhaler device architecture and the main inventive conversion mechanism from axial/linear trigger motion to rotational motion for advancing a blister strip. The dependent claims listed in the provided material refine multiple structural and motion-related features in that mechanism.
Axial/linear trigger converted to rotational main drum drive
A dry powder inhaler device with a trigger moving in an axial/linear direction, an actuator plate with a socket, and a transmission wheel converting the axial/linear motion of the trigger into rotational motion of the transmission wheel and transferring this rotational motion to a main drum that advances a blister strip for drug administration.
Actuator-plate socket meshing teeth transfer motion
An actuator plate having a second end comprising a socket sufficiently large to receive a transmission wheel therein, with a series of teeth aligned in the socket in the axial/linear direction in which the trigger is moved, wherein the transmission wheel meshes with the series of teeth.
Main drum disposed coaxially with transmission wheel
The main drum is disposed on and substantially coaxially with the transmission wheel, and the transmission wheel meshes with the series of teeth aligned in the socket of the actuator plate.
Blister strip layers wound to enable next-cavity administration
A main drum into which a blister strip having drug-carrying cavities is placed, a gear set enabling a drug in the next cavity of the blister strip to be administered by rotating the main drum and around which a protective layer or cover of the blister strip is wound, and additional gears in connection with the main drum around which a main layer of the blister strip is wound.
Barriers limiting actuator-plate displacement
The dry powder inhaler device includes barriers on an inner surface of the body to limit how much the actuator plate can be displaced.
Pretensioned spring return for trigger
The dry powder inhaler device includes a compressed helical pretension spring to return the trigger to an initial position after the trigger is moved and released.
Tooth and toothless edges on actuator plate
The actuator plate has a series of teeth aligned on a first edge of the plate and a toothless edge substantially opposite the first edge.
Toothless surface section on transmission wheel
The transmission wheel includes a toothless surface section.
Directional timing of transmission-wheel rotation versus main-drum rotation
As the trigger moves axially/linearly in and out, the transmission wheel rotates in two different directions at different times while the main drum rotates in a single direction.
Across the provided independent claim and dependent refinements, coverage centers on an actuator plate and transmission wheel that mesh with aligned teeth to convert axial/linear trigger movement into rotational motion for a coaxially disposed main drum. The claim set further refines layered blister-strip winding, trigger return using a compressed helical pretension spring, and structural features such as actuator-plate tooth/toothless edges and a toothless surface section on the transmission wheel, plus directional timing behavior and internal barriers limiting actuator-plate displacement.
Stated Advantages
Reduced required trigger force.
Accurate single-dose administration.
Reduced gear wear/breakage.
Automatic reset when the lid closes.
Documented Applications
A dry powder inhaler device using a blister advancement mechanism to administer a drug dose from a blister strip by rotating a main drum and around which blister strip layers are wound.
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