Methods, systems, and devices for monitoring anisocoria and asymmetry of pupillary reaction to stimulus

Inventors

Siminou, Kamran • Privitera, Claudio

Assignees

Neuroptics Inc

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Publication Number

US-10154783-B2

Patent

Publication Date

2018-12-18

Expiration Date


Abstract

A computer program is disclosed for performing the following method: recording images of a response of a left pupil to a stimulus thereby resulting in a first set of sequential images; recording images of a response of a right pupil to the same stimulus at the same time as the first images were recorded, thereby resulting in a second set of sequential images; displaying on a display simultaneously the first set of images and the second set of image, wherein the two sets of images are synchronized, and wherein a center of the left pupil of each image from the first set of sequential images is aligned with a center of the right pupil from the second set of sequential images on the display.

Core Innovation

The invention performs pupillometry monitoring of anisocoria and asymmetric pupillary light response using a handheld pupillometer. It records pupillary response images of a left pupil and a right pupil to the same stimulus at the same time, producing a first set of sequential images and a second set of sequential images corresponding to the left and right pupils, respectively.

The invention simultaneously displays the first set of images and the second set of images on a display. The two sets of images are synchronized, and the center of the left pupil of each image from the first set is aligned with the center of the right pupil from the second set on the display. This alignment is performed frame-by-frame as the sequential images are displayed.

The invention adds a visualization that generates a pair of parallel lines extending between the perimeter of the left pupil and the perimeter of the right pupil in each image. The parallel lines have a first section and a second section, where the distance between the parallel lines in the first section is defined by the diameter of the left pupil for each image, and the distance in the second section is defined by the diameter of the right pupil for each image.

Claims Coverage

The independent claim covers a program product that synchronizes and simultaneously displays left-pupil and right-pupil response images to the same stimulus, aligns pupil centers frame-by-frame, and generates a parallel-lines visualization with section-dependent spacing based on each pupil diameter. It includes two inventive features.

Synchronized simultaneous left/right pupil response display with center alignment

Recording images of a left pupil response to a stimulus as a first set of sequential images; recording images of a right pupil response to the same stimulus at the same time as the first images as a second set of sequential images; displaying simultaneously the first set and the second set on a display; synchronizing the two sets; and aligning a center of the left pupil of each image with a center of the right pupil on the display.

Parallel lines visualization with section-dependent spacing by pupil diameter

Generating a pair of parallel lines extending from the perimeter of the left pupil to the perimeter of the right pupil in each image; the parallel lines having a first section and a second section; where in the first section the distance between the parallel lines is defined by the diameter of the left pupil for each image and in the second section the distance between the parallel lines is defined by the diameter of the right pupil for each image.

Overall, the claim coverage focuses on synchronized simultaneous left and right pupil image sets aligned by pupil centers and a parallel-lines graphical representation spanning between left and right pupil perimeters with spacing in separate sections defined by each pupil’s diameter.

Stated Advantages

Not explicitly described in patent.

Documented Applications

Not explicitly described in patent.

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