Biopolymer-based emulsion lubricants for syringe barrels
Inventors
Gertz, Frederick Talley • Noolandi, Jaan • Schultheis, Robert James
Assignees
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Publication Number
US-10143804-B2
Publication Date
2018-12-04
Expiration Date
Abstract
A stable biopolymer-based emulsion lubricant including Agar is provided to reduce the friction between a syringe barrel plunger and the interior surface of the syringe barrel. According to exemplary embodiments the emulsion has a friction of less than 4N, the emulsion is temperature stable in a range of 4-23 degrees Celsius and the emulsion is stable for a period of at least 60 days.
Core Innovation
A medical drug delivery device includes a syringe barrel whose interior surface is lubricated with an emulsion of a hydrophobic liquid oil in a matrix of water-soluble polysaccharides. One type of the polysaccharides is Agar, and the emulsion lubricant is configured so that the interior surface of the syringe barrel is lubricated by the emulsion.
The emulsion is characterized by performance targets including emulsion friction of less than 4 N and temperature stability in a range from 4 to 23 degrees Celsius. The emulsion is also described as stable for at least 60 days.
A method is also described for lubricating a medical drug delivery device by spraying the emulsion onto the interior surface of a syringe barrel. The sprayed emulsion comprises hydrophobic liquid oil on a matrix of water-soluble polysaccharides, with Agar as one polysaccharide type.
Claims Coverage
Two independent claims are identified. Each centers on an emulsion with hydrophobic liquid oil dispersed in a water-soluble polysaccharide matrix containing Agar, with one claim directed to a lubricated syringe barrel and one claim directed to spraying the emulsion onto the barrel interior surface.
A syringe barrel lubricated with an Agar-based polysaccharide emulsion
A medical drug delivery device comprising a syringe barrel with an interior surface lubricated with an emulsion of a hydrophobic liquid oil in a matrix of water-soluble polysaccharides, wherein one type of the polysaccharides is Agar.
Spraying an Agar-based hydrophobic oil polysaccharide emulsion onto the syringe barrel interior
A method of lubricating a medical drug delivery device, comprising spraying an emulsion onto the interior surface of a syringe barrel, wherein the emulsion comprises a hydrophobic liquid oil on a matrix of water-soluble polysaccharides, wherein one type of the polysaccharides is Agar.
The independent claims cover lubrication of a syringe barrel interior surface using an emulsion of hydrophobic liquid oil in a water-soluble polysaccharide matrix where Agar is one polysaccharide type, including both the lubricated device and the spraying method.
Stated Advantages
Emulsion friction of less than 4 N.
Temperature stability in the range of 4 to 23 degrees Celsius.
Stability for at least 60 days.
Documented Applications
Lubricating a medical drug delivery device by lubricating the interior surface of a syringe barrel, including by spraying an emulsion onto the syringe barrel interior surface.
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