Production procedure for a functional feed based in ellagic acid, cimenol and alliin from vegetable extracts to be used as pronutrient in animal feed

Inventors

Borrell, Jaime Valls

Assignees

Biovet SA

Interested in licensing this patent?

MTEC can help explore whether this patent might be available for licensing for your application.

Publication Number

US-10111449-B2

Patent

Publication Date

2018-10-30

Expiration Date


Abstract

Obtention of aromatic compounds extracted from Punica granatum, Thymus vulgaris and Allium sativum and which have genome interaction capacity for regeneration of the enterocyte, and their use in the manufacture of functional additives for use in animal feed.

Core Innovation

The invention relates to a functional animal food pronutrient system formed from botanical extracts of Thymus vulgaris, Punica granatum and Allium sativum, with specified constituent ranges for p-cimenol, allin and ellagic acid. The system is described as targeting intestinal enterocyte regeneration in swine intestinal cells and as inducing an effect on the reproduction rate of RNA-protein in swine intestinal cells.

The functional rationale described includes genome interaction directed to intestinal enterocyte regeneration, together with antimicrobial/antiparasitic functions attributed to cimenol. The botanical selection is described as pairing cimenol from Thymus vulgaris with ellagic acid from Punica granatum and alliin/alliinase-related conversion associated with Allium sativum constituents.

The invention further describes manufacturing into a concentrated and standardized botanical extract preparation, followed by mixing into a liquid or powdered feed supplement. The composition is provided with minimum constituent percentages for ellagic acid, cimenol and alliin, and one claimed product includes treatment with methanolic hydrochloric acid.

Claims Coverage

The provided portion includes three independent claims that cover an animal food product consisting essentially of specified botanical extracts, with defined constituent content ranges and a stated inductor effect on the reproduction rate of RNA-protein in swine intestinal cells. The main variations are whether methanolic hydrochloric acid treatment is required and whether the claim text includes it in the scope alongside the inductor effect.

Botanical extract-based animal food product with inductor effect

An animal food product consisting essentially of an extract of Thymus vulgaris, an extract of Punica granatum and an extract of Allium sativum, wherein Thymus vulgaris has a p-cimenol content of 15%-17% by weight, Allium sativum has an allin content of 20%-26% and Punica granatum has an ellagic acid from 2%-4%, wherein said animal food product has an inductor effect on the reproduction rate of RNA-protein in swine intestinal cells.

Methanolic hydrochloric acid-treated extract product

An animal food product consisting essentially of an extract of Thymus vulgaris, an extract of Punica granatum and an extract of Allium sativum, wherein the Thymus vulgaris has a p-cimenol content of 15%-17% by weight, the Allium sativum has an allin content of 20%-26% and the Punica granatum has an ellagic acid from 2%-4%, wherein said animal food product was treated with methanolic hydrochloric acid.

Methanolic hydrochloric acid-treated extract product with RNA-protein reproduction-rate induction

An animal food product consisting essentially of an extract of Thymus vulgaris, an extract of Punica granatum and an extract of Allium sativum, wherein the Thymus vulgaris has a p-cimenol content of 15%-17% by weight, the Allium sativum has an allin content of 20%-26% and the Punica granatum has an ellagic acid from 2%-4%, wherein said animal food product was treated with methanolic hydrochloric acid and wherein said product has an inductor effect on the reproduction rate of RNA-protein in swine intestinal cells.

Across the independent claims, the invention is directed to an animal food product consisting essentially of extracts of Thymus vulgaris, Punica granatum and Allium sativum with defined p-cimenol, allin and ellagic acid ranges, optionally including treatment with methanolic hydrochloric acid. The functional scope includes an inductor effect on the reproduction rate of RNA-protein in swine intestinal cells.

Stated Advantages

Inductor effect on the reproduction rate of RNA-protein in swine intestinal cells.

Functional targeting of intestinal enterocyte regeneration via genome interaction.

Antimicrobial/antiparasitic functions attributed to cimenol.

Preservation of alliin/alliinase to enable in-mouth conversion.

Documented Applications

An animal food product used as a functional animal-feed pronutrient system intended for swine intestinal cells, with an inductor effect on the reproduction rate of RNA-protein.

JOIN OUR MAILING LIST

Stay Connected with MTEC

Keep up with active and upcoming solicitations, MTEC news and other valuable information.