Nutritional supplements for improving female fertility
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Publication Number
US-10092545-B2
Publication Date
2018-10-09
Expiration Date
Abstract
The present invention relates to a fertility-enhancing composition for human male fertility therapy and a method for using the same to improve or enhance human male fertility. The nutritional supplement composition of the invention includes an effective amount of L-carnitine tartrate, coenzyme Q10, methylcobalamin, N-acetyl L-cysteine, and grape seed extract.
Core Innovation
The invention relates to a hormone-free single-unit nutritional supplement regimen for improving female fertility. The problem addressed is difficulty conceiving, where oxidative stress affects egg quality and ovarian function. The regimen is directed to a female human using a defined combination of inositols and additional fertility-related nutrients.
The core composition includes myo-inositol, d-chiro-inositol, melatonin, N-acetyl L-cysteine (NAC), coenzyme Q10, Resveratrol, Choline, and Benfotiamine. Embodiments further include optional antioxidant nutrients such as alpha-lipoic acid, grape seed extract, and trans-resveratrol along with additional vitamins and minerals.
The disclosed use includes supplementation prior to natural conception or assisted reproductive technologies, with an intended preconception duration. An efficacy study outline is described by comparing a placebo control with supplementation in women with difficulty conceiving, to assess expected improvement in conception rates.
Claims Coverage
The independent claim covers a single-unit nutritional supplement composition for improving female fertility using one effective combination of inositols plus melatonin, NAC, Resveratrol, Choline, Benfotiamine, and coenzyme Q10. The dependent claims add multiple inventive refinements, including ingredient ratio constraints, quantitative thresholds, and narrowing administration timing and frequency.
Single-unit nutritional supplement composition for improving female fertility
A single unit nutritional supplement composition for improving female fertility comprising an effective amount of a combination of myo-inositol, d-chiro-inositol, melatonin, n-acetyl 1-cysteine, Resveratrol, Choline, Benfotiamine, and coenzyme Q10.
Myo-inositol to d-chiro-inositol ratio constraint
The ratio of myo-inositol to d-chiro-inositol is about 40:1.
Minimum N-acetyl L-cysteine amount in the single unit
A single-unit nutritional supplement composition comprises at least 25 mg of N-acetyl L-cysteine.
Additional mineral and related ingredient options
The nutritional supplement composition further comprises iron, selenium, zinc, copper, manganese, chromium, molybdenum, boron, choline bitartrate, or a combination thereof.
Preconception administration duration
The composition is administered to said female human for at least 3 months prior to conception.
Per-day unit dosage frequency
The composition is administered one to six unit dosage formulation per day to said female human.
Overall claim coverage is centered on a single-unit, hormone-free nutritional supplement composition that improves female fertility through a defined combination of myo-inositol and d-chiro-inositol with melatonin, N-acetyl L-cysteine, Resveratrol, Choline, Benfotiamine, and coenzyme Q10, and is further narrowed by ratio and dosage thresholds plus preconception timing and per-day unit dosage frequency constraints.
Stated Advantages
Improving female fertility.
Reducing oxidative stress affecting egg quality and ovarian function.
Expected improvement in conception rates compared to placebo in women with difficulty conceiving.
Documented Applications
Supplementation prior to natural conception or assisted reproductive technologies.
An efficacy study in women with difficulty conceiving, comparing placebo control versus supplementation to assess improvement in conception rates.
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