Portable testing device for analyzing biological samples
Inventors
Baumgartner, Mark B. • Hodgson, Cory D. • Bristow, Andrew L. • Syverson, Paul A. • Pexsa, Grant L. • Davis, Christopher T. • Schoeneck, Rich • Brown, Duane • Cook, Darren
Assignees
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Publication Number
US-10036058-B2
Publication Date
2018-07-31
Expiration Date
Abstract
A portable testing device includes a housing with an integrated touchscreen display and a receptacle in which a sample holder containing a biological sample and reagent mixture can be placed. The portable testing device further includes an optical assembly positioned in the housing, an electronic assembly that is configured to receive data from the optical assembly and transmit it for display on the touchscreen display, and a power supply in the housing to power the portable testing device. The optical assembly includes an excitation filter that extends across the entire optical assembly and an emission filter that extends across the entire optical assembly.
Core Innovation
The invention provides a portable testing device that includes a housing having an integrated touchscreen display and a receptacle configured to receive a sample holder containing a biological sample and reagent mixture. The device further includes an optical assembly positioned in the housing, where the optical assembly is configured to amplify and detect a signal from the biological sample and reagent mixture in the sample holder. The optical assembly includes an excitation filter extending across at least a portion of an entire-optical assembly and an emission filter extending across at least a portion of the entire-optical assembly.
The optical assembly includes a sample block with cavities shaped to receive the sample holder and a heating component configured to heat the biological sample and reagent mixture. A first housing portion is positioned on a first side of the sample block, with the first excitation filter and the first emission filter positioned in the first housing portion. The first housing portion further includes a first plurality of light-emitting diodes positioned on a first side of the first excitation filter and a first plurality of photodetectors positioned on a first side of the first emission filter.
A second housing portion is positioned on a second side of the sample block, where the second housing portion includes a second excitation filter positioned in the second housing portion and a second plurality of light-emitting diodes positioned on a first side of the second excitation filter. The second housing portion further includes a second emission filter positioned in the second housing portion and a second plurality of photodetectors positioned on a first side of the second emission filter. The device also includes an electronic assembly configured to receive data from the optical assembly and transmit it for display on the touchscreen display, and a power supply in the housing to power the portable testing device.
Claims Coverage
The document explicitly provides one independent claim (clm-00001). Its claim coverage centers on a portable, touchscreen-equipped testing device with an optical assembly that amplifies and detects a signal using excitation and emission filters that extend across an entire-optical assembly, combined with a heated sample block and housing portions that mount LED and photodetector pluralities on opposite sides of the sample block.
Portable testing device with integrated touchscreen receptacle and optical signal amplification/detection
A portable testing device including a housing with an integrated touchscreen display and a receptacle configured to receive a sample holder containing a biological sample and reagent mixture, and an optical assembly positioned in the housing that is configured to amplify and detect a signal from the biological sample and reagent mixture in the sample holder.
Excitation and emission filters extending across an entire-optical assembly
The optical assembly includes a first excitation filter that extends across at least a portion of the entire-optical assembly and a first emission filter that extends across at least a portion of the entire-optical assembly.
Heated sample block with cavities shaped to receive the sample holder
The optical assembly comprises a sample block in which the sample holder can be positioned, where the sample block includes a plurality of cavities shaped to receive the sample holder and a heating component configured to heat the biological sample and reagent mixture in the sample holder.
Opposed housing portions with excitation filter and LED on one side, photodetectors on the same side
A first housing portion on a first side of the sample block has the first excitation filter and the first emission filter positioned in the first housing portion, the first plurality of light-emitting diodes positioned on a first side of the first excitation filter, and the first plurality of photodetectors positioned on a first side of the first emission filter.
Opposed housing portion with excitation filter and LED on one side, photodetectors on the same side
A second housing portion on a second side of the sample block includes a second excitation filter positioned in the second housing portion, a second plurality of light-emitting diodes positioned on a first side of the second excitation filter, a second emission filter positioned in the second housing portion, and a second plurality of photodetectors positioned on a first side of the second emission filter.
Electronic assembly for transmitting optical assembly data to touchscreen display with in-housing power
An electronic assembly configured to receive data from the optical assembly and transmit it for display on the touchscreen display, and a power supply in the housing to power the portable testing device.
The independent claim provides a unified portable device architecture: touchscreen housing and receptacle for a sample holder containing a biological sample and reagent mixture, an optical assembly that amplifies and detects a signal using excitation and emission filters spanning an entire-optical assembly, a heated sample block with cavities for the sample holder, and opposed housing portions carrying LED and photodetector pluralities relative to excitation and emission filters, with an electronic assembly for displaying acquired data.
Stated Advantages
Reduced contamination and degradation (field-use advantages).
Rapid decision-making.
Safety response.
Documented Applications
Portable biological testing in a field-use context with real-time reaction data display and logging.
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