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Publication Number
US-10022413-B2
Publication Date
2018-07-17
Expiration Date
Abstract
In one embodiment, the present application provides an herbal supplement and method for treating bloating, constipation and/or weight gain in a human subject comprising orally administering to a subject in need thereof an effective amount of the herbal supplement comprising a red quebracho extract. In other embodiments, the supplement may additionally include a triterpenoid saponin, an anti-spasmodic agent, or both.
Core Innovation
The invention relates to a method for treating bloating, constipation and/or weight gain in a human subject by orally administering an effective amount of a herbal supplement. The herbal supplement comprises a red quebracho extract, an herbal composition comprising a triterpenoid saponin, and an anti-spasmodic agent, and may be formulated as tablets or capsules with a nutraceutically acceptable carrier.
The red quebracho extract is present between about 0.5% to about 75% by weight of the total supplement, the herbal composition comprising the triterpenoid saponin is present between about 10% to about 90% by weight, and the anti-spasmodic agent is present between about 2% to about 70% by weight. In specific embodiments, the anti-spasmodic agent is peppermint oil and the triterpenoid saponin is provided as a plant extract from Aesculus or Satindus, including Aesculus hippocastanum.
The disclosed rationale links administration of condensed tannins associated with red quebracho extract to reductions in methane and methanogenic bacteria and/or methanogenic archaebacteria, and to effects on gut microbiota and energy regulation. The document discusses the relationship between gut microbiota, small intestinal bacterial overgrowth (SIBO), and the treatment of bloating, constipation, and/or weight gain, and includes an example single-blinded placebo-controlled study in 20 patients evaluating bloating and gas, constipation, safety, and weight changes.
Claims Coverage
The document provides two independent claims covering orally administered herbal supplement methods for treating bloating, constipation and/or weight gain. Each independent claim centers on a multi-component herbal formulation including red quebracho extract plus a triterpenoid saponin-containing herbal composition and an anti-spasmodic agent, with defined composition or dosage-form ranges.
Orally administering a red quebracho extract, triterpenoid saponin composition and anti-spasmodic agent with defined weight-percentage ranges
Orally administering an effective amount of a herbal supplement comprising a red quebracho extract, an herbal composition comprising a triterpenoid saponin, and an anti-spasmodic agent, wherein the red quebracho extract is present between about 0.5% to about 75% by weight of the total supplement, the herbal composition is present between about 10% to about 90% by weight of the total supplement, and the anti-spasmodic agent is present between about 2% to about 70% by weight of the total supplement.
Oral tablets or capsules containing red quebracho extract with a triterpenoid saponin composition and anti-spasmodic agent within defined mg ranges
Orally administering an effective amount of a herbal supplement comprising a red quebracho extract, a nutraceutically acceptable carrier, and one or more herbal compositions comprising a triterpenoid saponin and an anti-spasmodic agent, wherein the herbal supplement is in the form of one or more tablets or capsules and the dosage form comprises 10 to 1000 mg red quebracho extract, 50-2000 mg herbal composition comprising a triterpenoid saponin, and 10-1000 mg anti-spasmodic agent.
Overall, the claim coverage is directed to combination herbal supplement treatments that pair red quebracho extract with a triterpenoid saponin-containing herbal composition and an anti-spasmodic agent, either by specified weight-percentage ranges of the components or by specified tablet/capsule dosage-form mg ranges, with additional refinements described in dependent claims for peppermint oil and named triterpenoid-saponin plant sources.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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