X-Therma
X-Therma pioneers a breakthrough biopreservation platform, transforming “living” medicines into on demand treatments. They develop innovative solutions to extend the preservation time of cells, tissues, and organs at below-freezing temperatures, aiming to improve patient outcomes and address global organ availability issues. Their mission is to create time by emulating and improving upon natural processes to enable long-term storage and transportation of biological materials.
Industries
Nr. of Employees
small (1-50)
X-Therma
North America: 625 Alfred Nobel Drive, Suite B, Hercules, CA 94547, USA; Europe: Langer Weg 11, 6020 Innsbruck, Austria
Patents
Products
DMSO-free cGMP cryopreservation media for cells and tissues
Chemically defined, non-toxic cryoprotectant formulations for storage of cells and tissues at ultra-low temperatures; offered in clinical/cGMP grade with sterile production controls.
Organ preservation solution for high subzero multi-day storage
Preservation solution formulated to limit ice formation and reduce metabolic/ischemic injury during controlled high subzero storage, demonstrated for multi-day organ viability.
Sensor-enabled passive organ transport device
Portable transport hardware that maintains preservation conditions passively (without external power or perfusion) and includes sensors for temperature stabilization and transit monitoring.
DMSO-free cGMP cryopreservation media for cells and tissues
Chemically defined, non-toxic cryoprotectant formulations for storage of cells and tissues at ultra-low temperatures; offered in clinical/cGMP grade with sterile production controls.
Organ preservation solution for high subzero multi-day storage
Preservation solution formulated to limit ice formation and reduce metabolic/ischemic injury during controlled high subzero storage, demonstrated for multi-day organ viability.
Sensor-enabled passive organ transport device
Portable transport hardware that maintains preservation conditions passively (without external power or perfusion) and includes sensors for temperature stabilization and transit monitoring.
Services
Provision of chemically defined, DMSO-free cryopreservation media manufactured for clinical and commercial use in multiple packaging scales.
Turnkey solutions combining preservation solutions and transport hardware for extended-duration subzero organ storage and long-distance transfers, including sensor-based monitoring capabilities.
Research collaborations to evaluate preservation formulations, perform comparative analytical assessments, and conduct preclinical transplantation studies.
Provision of chemically defined, DMSO-free cryopreservation media manufactured for clinical and commercial use in multiple packaging scales.
Turnkey solutions combining preservation solutions and transport hardware for extended-duration subzero organ storage and long-distance transfers, including sensor-based monitoring capabilities.
Research collaborations to evaluate preservation formulations, perform comparative analytical assessments, and conduct preclinical transplantation studies.
Expertise Areas
- Biopreservation chemistry
- Cryoprotectant formulation development
- High subzero organ preservation
- Organ transport and cold-chain logistics
Key Technologies
- Peptoid/peptidomimetic antifreeze polymers
- Synthetic ice-interactive cryoprotectants
- DMSO-free chemically defined cryopreservation media
- Ultra-low temperature storage methods (-70°C to -196°C)
News & Updates
Surgeons successfully transported pig kidneys between Baltimore and Innsbruck five times using X-Therma's FDA Breakthrough-designated subzero preservation technology.
X-Therma Inc. has achieved GMP (Good Manufacturing Practice) commercial readiness with its flagship product, XT-Thrive®.
Discussion on advances in the treatment of type 1 diabetes and the potential of cryopreservation technologies to improve accessibility.
An article about biotech advances transforming organ preservation and transport.
X-Therma Inc. received 1st place in the 2018 SVIEF Star Award competition.
Surgeons successfully transported pig kidneys between Baltimore and Innsbruck five times using X-Therma's FDA Breakthrough-designated subzero preservation technology.
X-Therma Inc. has achieved GMP (Good Manufacturing Practice) commercial readiness with its flagship product, XT-Thrive®.
Discussion on advances in the treatment of type 1 diabetes and the potential of cryopreservation technologies to improve accessibility.
An article about biotech advances transforming organ preservation and transport.
X-Therma Inc. received 1st place in the 2018 SVIEF Star Award competition.