X-Therma


X-Therma pioneers a breakthrough biopreservation platform, transforming “living” medicines into on demand treatments. They develop innovative solutions to extend the preservation time of cells, tissues, and organs at below-freezing temperatures, aiming to improve patient outcomes and address global organ availability issues. Their mission is to create time by emulating and improving upon natural processes to enable long-term storage and transportation of biological materials.

Industries

biotechnology
health-care
life-science

Nr. of Employees

small (1-50)

X-Therma

Richmond, California, United States, North America


Products

DMSO-free cGMP cryopreservation media for cells and tissues

Chemically defined, non-toxic cryoprotectant formulations for storage of cells and tissues at ultra-low temperatures; offered in clinical/cGMP grade with sterile production controls.

Organ preservation solution for high subzero multi-day storage

Preservation solution formulated to limit ice formation and reduce metabolic/ischemic injury during controlled high subzero storage, demonstrated for multi-day organ viability.

Sensor-enabled passive organ transport device

Portable transport hardware that maintains preservation conditions passively (without external power or perfusion) and includes sensors for temperature stabilization and transit monitoring.


Services

Commercial supply of cGMP cryopreservation media

Provision of chemically defined, DMSO-free cryopreservation media manufactured for clinical and commercial use in multiple packaging scales.

Integrated organ preservation and transport solutions

Turnkey solutions combining preservation solutions and transport hardware for extended-duration subzero organ storage and long-distance transfers, including sensor-based monitoring capabilities.

Collaborative R&D and preclinical testing partnerships

Research collaborations to evaluate preservation formulations, perform comparative analytical assessments, and conduct preclinical transplantation studies.

Expertise Areas

  • Biopreservation chemistry
  • Cryoprotectant formulation development
  • High subzero organ preservation
  • Organ transport and cold-chain logistics
  • Show More (4)

Key Technologies

  • Peptoid/peptidomimetic antifreeze polymers
  • Synthetic ice-interactive cryoprotectants
  • DMSO-free chemically defined cryopreservation media
  • Ultra-low temperature storage methods (-70°C to -196°C)
  • Show More (5)

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