Virometix


Virometix AG is a Swiss biotechnology company focused on discovering and developing fully synthetic vaccines for infectious diseases and cancer. They utilize a proprietary modular and fully synthetic nanoparticle technology platform to create safe, effective, and scalable vaccines. Their lead indication targets Streptococcus pneumoniae infections, addressing a high unmet medical need. The company's approach involves structure-based vaccines designed to elicit precise, robust, and sustained immune responses, with advantages over traditional vaccine methods including safety, simplicity, and cost-effectiveness.

Industries

biotechnology
health-care
medical

Nr. of Employees

small (1-50)

Virometix

Wagistrasse 14, 8952 Schlieren, Switzerland


Patents

Cyclic peptides for protection against respiratory syncytial virus

US-11680085-B2

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Proline-rich peptides protective against S. pneumoniae

US-9943583-B2

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Products

V-212 (peptide-based serotype-independent pneumococcal vaccine candidate)

Peptide-epitope vaccine candidate based on conserved pneumococcal surface protein domains presented on synthetic virus-like particles; preclinical models demonstrated serotype-independent antibody recognition and protection in mouse sepsis models.

V-306 (epitope-specific nanoparticle RSV vaccine candidate)

Epitope-focused nanoparticle vaccine candidate targeting a neutralizing epitope on RSV F protein; evaluated in a Phase I randomized, placebo-controlled, dose-escalating study with reported safety and immunogenicity.

Coronaviruses prophylactic vaccine candidates

Epitope-focused nanoparticle candidates targeting conserved regions of coronavirus spike proteins and including protective T-cell epitopes from multiple viral proteins, intended for broad protection across coronaviruses.

Cancer vaccine candidates (SVLP-based therapeutic approaches)

Programmes applying multivalent synthetic nanoparticle delivery to cancer antigens intended to elicit cytotoxic T-cell responses for therapeutic vaccination.


Services

Co-development partnerships applying synthetic nanoparticle platform to vaccines and other applications; licensing of platform IP and collaborative R&D.

Collaborative work on formulation of biologics and peptides, drug delivery approaches and monoclonal antibody development using the nanoparticle platform.

Expertise Areas

  • Peptide-based vaccine development
  • Structure-guided/epitope-focused vaccine design
  • Nanoparticle (SVLP) vaccine delivery
  • Preclinical infectious disease models and in vivo efficacy
  • Show More (5)

Key Technologies

  • Synthetic virus-like particles (self-assembling lipopeptide nanoparticles)
  • Conformational epitope-mimetic peptides and glycopeptides
  • Solid-phase peptide synthesis (SPPS)
  • AI-driven antigen identification and in silico design
  • Show More (6)

News & Updates

Presentations on SARS-CoV-2 vaccine candidates and pneumococcal vaccines.

Presentation of V-212, a peptide-based vaccine candidate against Streptococcus pneumoniae.

Discussion of V-212, a peptide-based vaccine against Streptococcus pneumoniae.

Presentation of V-212, a peptide-based vaccine candidate against Streptococcus pneumoniae.

Discussion on engineered synthetic virus-like particles for antigen delivery.

Presentation of V-212, a peptide-based vaccine candidate against Streptococcus pneumoniae.

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