Vala Sciences, Inc.
Vala Sciences is a pioneering biotechnology company based in San Diego, California, specializing in high-speed video microscopy instruments and assays for single-cell analysis. The company's mission is to improve drug discovery and development by providing advanced imaging platforms, assays, and services that enable precise understanding of cellular responses to drug compounds. Vala's innovative platform, including the Kinetic Image Cytometer (KIC®), CyteSeer® analysis software, and ValaDATE™ AI platform, supports pharmaceutical, academic, and government research to develop safer and more effective therapeutics. With a history of collaborations, publications, and centers of excellence, Vala Sciences aims to revolutionize preclinical drug screening and predictive modeling of human clinical outcomes.
Industries
Nr. of Employees
small (1-50)
Vala Sciences, Inc.
6370 Nancy Ridge Dr. #106, San Diego, CA 92121
Patents
Analysis of action potentials, transients, and ion flux in excitable cells
US-10928308-B2
View DetailsAnalysis of action potentials, transients, and ion flux in excitable cells
US-10359357-B2
View DetailsSystem and method for automatic color segmentation and minimum significant response for measurement of fractional localized intensity of cellular compartments
US-8116982-B2
View DetailsUser interface method and system for management and control of automated image processing in high content screening or high throughput screening
US-8107711-B2
View DetailsSystem, method, and kit for processing a magnified image of biological material to identify components of a biological object
US-7933435-B2
View Details
Analysis of action potentials, transients, and ion flux in excitable cells
US-10928308-B2
View DetailsAnalysis of action potentials, transients, and ion flux in excitable cells
US-10359357-B2
View DetailsSystem and method for automatic color segmentation and minimum significant response for measurement of fractional localized intensity of cellular compartments
US-8116982-B2
View DetailsUser interface method and system for management and control of automated image processing in high content screening or high throughput screening
US-8107711-B2
View DetailsSystem, method, and kit for processing a magnified image of biological material to identify components of a biological object
US-7933435-B2
View DetailsProducts
High-speed kinetic imaging cytometer (plate-based video microscope)
Automated plate-compatible imaging system that captures millisecond-resolution videos of live cells for kinetic measurements (voltage, calcium, contractility) and supports multiple objectives, environmental control and stimulation modules.
Automated video analysis software for single-cell kinetics
Desktop and pipeline software that segments cells, extracts per-cell and per-transient kinetic traces, parameterizes transient features, and aggregates large-scale results for statistical comparison.
AI-powered analytics for toxicity and efficacy
Machine-learning platform that analyzes billions of extracted parameters and compares experimental kinetic signatures to a reference library of human cell-response waveforms for toxicity and efficacy prediction.
Structured illumination microscopy system for higher-resolution imaging
Microscopy system providing structured illumination to achieve confocal-class spatial resolution at acquisition speeds suitable for screening workflows.
Validated hiPSC-derived cells and reagent kits
Catalog of validated human iPSC-derived cell products (e.g., microglia) and reagent kits, antibodies and control extracts for use in imaging and biochemical assays.
High-speed kinetic imaging cytometer (plate-based video microscope)
Automated plate-compatible imaging system that captures millisecond-resolution videos of live cells for kinetic measurements (voltage, calcium, contractility) and supports multiple objectives, environmental control and stimulation modules.
Automated video analysis software for single-cell kinetics
Desktop and pipeline software that segments cells, extracts per-cell and per-transient kinetic traces, parameterizes transient features, and aggregates large-scale results for statistical comparison.
AI-powered analytics for toxicity and efficacy
Machine-learning platform that analyzes billions of extracted parameters and compares experimental kinetic signatures to a reference library of human cell-response waveforms for toxicity and efficacy prediction.
Structured illumination microscopy system for higher-resolution imaging
Microscopy system providing structured illumination to achieve confocal-class spatial resolution at acquisition speeds suitable for screening workflows.
Validated hiPSC-derived cells and reagent kits
Catalog of validated human iPSC-derived cell products (e.g., microglia) and reagent kits, antibodies and control extracts for use in imaging and biochemical assays.
Services
Contract execution of high-throughput live-cell kinetic and fixed-endpoint assays using hiPSC-derived models and automated imaging to assess toxicity and efficacy across compound libraries and doses.
Design and validation of bespoke live-cell and fixed-endpoint assays (voltage, calcium, contractility, morphology, protein localization) tailored to customer requirements and compatible with high-throughput formats.
Sale, installation and field support for automated high-speed imaging instruments and high-resolution microscopy systems, including software updates, training and maintenance.
Provision of validated hiPSC-derived cells, control extracts, antibodies and screening kits for use in imaging and biochemical assays.
Collaborative demonstrations and limited testing at partnered research centers using installed imaging systems to evaluate platform capabilities and workflows.
Contract execution of high-throughput live-cell kinetic and fixed-endpoint assays using hiPSC-derived models and automated imaging to assess toxicity and efficacy across compound libraries and doses.
Design and validation of bespoke live-cell and fixed-endpoint assays (voltage, calcium, contractility, morphology, protein localization) tailored to customer requirements and compatible with high-throughput formats.
Sale, installation and field support for automated high-speed imaging instruments and high-resolution microscopy systems, including software updates, training and maintenance.
Provision of validated hiPSC-derived cells, control extracts, antibodies and screening kits for use in imaging and biochemical assays.
Collaborative demonstrations and limited testing at partnered research centers using installed imaging systems to evaluate platform capabilities and workflows.
Expertise Areas
- High-content single-cell kinetic screening
- Assay development for hiPSC-derived disease models
- Image segmentation and transient parameterization
- Predictive preclinical safety and efficacy screening
Key Technologies
- High-speed video microscopy (millisecond-resolution imaging)
- Single-cell time-series fluorescence imaging
- sCMOS scientific cameras
- Structured illumination microscopy (SIM)
News & Updates
A strategic partnership to advance the 4MTx pipeline, supporting drug discovery and development.
Vala's platform and research have been cited extensively in scientific literature.
Vala has installations at Stanford, UCSF, Northwestern, Broad Institute, Baylor College of Medicine, and others.
A strategic partnership to advance the 4MTx pipeline, supporting drug discovery and development.
Vala's platform and research have been cited extensively in scientific literature.
Vala has installations at Stanford, UCSF, Northwestern, Broad Institute, Baylor College of Medicine, and others.