Unleash Immuno Oncolytics


Unleash Immuno Oncolytics is an immune-oncology company developing armed, oncolytic viruses that target both the tumor and the stromal compartment of cancers through multiple mechanisms of action in a single product. Their mission is to unleash the body's natural ability to eliminate malignant cells by disrupting tumor architecture and changing the tumor microenvironment, especially in metastatic disease where dense stromal tissue provides a refuge for malignant cells.

Industries

biotechnology
medical-device
therapeutics

Nr. of Employees

small (1-50)

Unleash Immuno Oncolytics

Saint Louis, Missouri, United States, North America


Patents

Oncolytic adenoviral vector and methods of use

US-11542526-B2

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Products

Oncolytic virus therapeutic candidate targeting tumor cells and tumor-associated stroma

A biologic therapeutic candidate based on a conditionally replicating viral vector designed to infect and replicate in both malignant cells and tumor-associated stromal cells, engineered to express multiple immunomodulatory cytokines to promote systemic anti-tumor immune responses and disrupt tumor architecture.

Expertise Areas

  • Oncolytic immunotherapy
  • Viral vector engineering
  • Tumor microenvironment and stroma targeting
  • Cytokine-based immunomodulation
  • Show More (1)

Key Technologies

  • Oncolytic virus engineering
  • Conditionally replicating viral vectors
  • Viral cytokine payload expression
  • Tumor stroma targeting strategies
  • Show More (1)

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