University of Massachusetts Chan Medical School
MassBiologics is a non-profit, FDA-licensed manufacturer of vaccines and biologic products, dedicated to improving public health through research, development, and production of biologics including vaccines, plasma derivatives, and monoclonal antibodies. Located in Boston, it has a mission of creating medicines for better lives and a vision to be a center of excellence in biologic medicines and technologies, serving both local and global communities.
Industries
Nr. of Employees
large (251-1000)
University of Massachusetts Chan Medical School
Products
Tetanus and Diphtheria (Td) toxoid vaccine (adsorbed)
Licensed vaccine product manufactured and distributed nationwide for routine immunization.
Licensed and investigational monoclonal antibody therapeutics
Portfolio of developed and partnered monoclonal antibody candidates and licensed antibody therapeutics for infectious and other indications; includes products at investigational and commercial stages.
Tetanus and Diphtheria (Td) toxoid vaccine (adsorbed)
Licensed vaccine product manufactured and distributed nationwide for routine immunization.
Licensed and investigational monoclonal antibody therapeutics
Portfolio of developed and partnered monoclonal antibody candidates and licensed antibody therapeutics for infectious and other indications; includes products at investigational and commercial stages.
Services
Development and validation of analytical assays to support characterization, release testing, and stability programs.
Cell line development and optimization for expression of biologic therapeutics to support process scale-up.
Preformulation and formulation development to improve product stability and manufacturability.
Design and optimization of downstream purification and concentration processes to produce clinical- and commercial-grade drug substance.
cGMP upstream and downstream production of bulk drug substance from cell culture systems for IND and commercial programs.
Creation and management of master and working cell banks under GMP to support consistent manufacturing.
Development and validation of analytical assays to support characterization, release testing, and stability programs.
Cell line development and optimization for expression of biologic therapeutics to support process scale-up.
Preformulation and formulation development to improve product stability and manufacturability.
Design and optimization of downstream purification and concentration processes to produce clinical- and commercial-grade drug substance.
cGMP upstream and downstream production of bulk drug substance from cell culture systems for IND and commercial programs.
Creation and management of master and working cell banks under GMP to support consistent manufacturing.
Expertise Areas
- Clinical trial supply and early-phase clinical support
- Biologics process development
- cGMP biologics manufacturing
- Monoclonal antibody and nanobody discovery
Key Technologies
- Monoclonal antibody production
- Nanobody and secretory IgA therapeutics
- Mammalian cell culture
- Bacterial expression systems