TissueGen


TissueGen is a company dedicated to developing next-generation drug delivery technologies that address unmet medical needs. They focus on creating life-changing treatment modalities for patients with both acute and chronic conditions, utilizing proprietary encapsulation technology to deliver complex therapeutics such as proteins, antibodies, and growth factors. Their platform enables the delivery of sensitive biologics using biodegradable fibers, microspheres, and other formats, with a strong emphasis on preserving biological activity and enabling extended release. The company has a rich heritage rooted in biomedical engineering research and holds a significant patent portfolio in the field of drug delivery.

Industries

biopharma
biotechnology
pharmaceutical

Nr. of Employees

small (1-50)

TissueGen


Patents

Methods and compositions for maintaining the conformation and structural integrity of biomolecules

US-12121560-B2

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Methods and compositions for maintaining the conformation and structural integrity of biomolecules

US-11197905-B2

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Drug-eluting self-retaining sutures and methods relating thereto

US-11007296-B2

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Methods and compositions for maintaining the conformation and structural integrity of biomolecules

US-10363281-B2

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Self-expanding medical device

US-8672996-B2

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Services

Development of polymeric extended‑release formulations for small molecules and biologics using formats such as microspheres and fibers.

Manufacture of wet‑extruded drug‑loaded biodegradable fibers suitable for weaving, knitting, braiding, or use as sutures with controlled release characteristics.

Formulation of microparticles to encapsulate water‑soluble drugs sized for administration through small‑gauge needles.

Production processes to generate nanoparticles that protect therapeutic agents and enable their incorporation into polymer solutions for downstream formulation.

Management and maintenance of patent families and related intellectual property across multiple jurisdictions.

Expertise Areas

  • Polymeric drug delivery
  • Extended‑release formulation design
  • Particle engineering (micro‑ and nano‑scale)
  • Encapsulation of biologics
  • Show More (4)

Key Technologies

  • Wet extrusion of polymeric fibers
  • Microsphere formulation
  • Drug‑loaded biodegradable fibers
  • Nanoparticle production
  • Show More (4)

News & Updates

A legal victory where TissueGen and the University of Texas System secured a $42 million patent infringement verdict against Boston Scientific.

TissueGen and the University of Texas System were awarded a $42 million verdict against Boston Scientific for patent infringement.


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