Think Bioscience
Think Bioscience is dedicated to developing small-molecule drugs for challenging targets using synthetic biology. Their mission is to create impactful medicines for diseases lacking effective treatments, leveraging innovative science and interdisciplinary teamwork to address undruggable proteins and complex biological challenges.
Industries
Nr. of Employees
small (1-50)
Think Bioscience
Products
Pocket-finding discovery platform
A discovery platform engineered to identify cryptic or conditionally exposed protein pockets to inform small-molecule discovery.
Microbially guided discovery and biosynthesis (publication)
Peer-reviewed research describing microbial-guided discovery and biosynthesis of biologically active natural products.
Evolution-guided biosynthesis of terpenoid inhibitors (publication)
Peer-reviewed research on using evolutionary guidance in biosynthetic systems to generate terpenoid inhibitors.
Genetically encoded detection of biosynthetic protease inhibitors (publication)
Peer-reviewed description of genetically encoded detection methods used to find biosynthetic protease inhibitors.
Pocket-finding discovery platform
A discovery platform engineered to identify cryptic or conditionally exposed protein pockets to inform small-molecule discovery.
Microbially guided discovery and biosynthesis (publication)
Peer-reviewed research describing microbial-guided discovery and biosynthesis of biologically active natural products.
Evolution-guided biosynthesis of terpenoid inhibitors (publication)
Peer-reviewed research on using evolutionary guidance in biosynthetic systems to generate terpenoid inhibitors.
Genetically encoded detection of biosynthetic protease inhibitors (publication)
Peer-reviewed description of genetically encoded detection methods used to find biosynthetic protease inhibitors.
Services
Partnership engagements to leverage synthetic-biology discovery platform and medicinal chemistry capabilities for target-focused small-molecule discovery.
Collaborative access to a discovery platform aimed at finding nonobvious binding pockets and guiding small-molecule development against challenging targets.
Partnership engagements to leverage synthetic-biology discovery platform and medicinal chemistry capabilities for target-focused small-molecule discovery.
Collaborative access to a discovery platform aimed at finding nonobvious binding pockets and guiding small-molecule development against challenging targets.
Expertise Areas
- Small-molecule drug discovery for undruggable targets
- Synthetic biology-enabled discovery
- Microbial biosynthesis and pathway engineering
- Genetically encoded library generation and screening
Key Technologies
- Synthetic biology
- Genetically encoded libraries
- Synthetic transcriptional circuits
- Microbial engineering
News & Updates
The company announced the extension of its seed funding round to further develop its pocket-finding platform.
Wendy Young, Ph.D., was appointed to the company's Scientific Advisory Board.
The company received a $1 million SBIR Phase II grant from NSF.
The company was awarded a $250,000 grant from OEDIT’s program.
The company announced additions to its leadership team.
The company was recognized as a finalist for an industry award.
The company announced the extension of its seed funding round to further develop its pocket-finding platform.
Wendy Young, Ph.D., was appointed to the company's Scientific Advisory Board.
The company received a $1 million SBIR Phase II grant from NSF.
The company was awarded a $250,000 grant from OEDIT’s program.
The company announced additions to its leadership team.
The company was recognized as a finalist for an industry award.