Thermedical


Thermedical is a private medical device company developing proprietary thermal ablation therapies aimed at treating large tissue volumes for conditions such as Ventricular Tachycardia (VT) and soft tissue tumors. Their innovative Thermedical Ablation System employs Saline-Enhanced Radio Frequency (SERF) energy to create durable, large, and predictable lesions, potentially offering more effective and safer treatments. The company is focused on advancing treatments for cardiac arrhythmias and cancer, with several products and clinical trials underway, including FDA clearances and breakthrough device designations.

Industries

biotechnology
health-care
medical-device

Nr. of Employees

small (1-50)


Patents

Devices and methods for delivering fluid to tissue during ablation therapy

US-12310651-B2

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Methods and devices for use of degassed fluids with fluid enhanced ablation devices

US-11950829-B2

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Inferred maximum temperature monitoring for irrigated ablation therapy

US-11918277-B2

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Methods and devices for controlling ablation therapy

US-11871979-B2

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Devices and methods for remote temperature monitoring in fluid enhanced ablation therapy

US-11583330-B2

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Methods and devices for use of degassed fluids with fluid enhanced ablation devices

US-11135000-B2

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Products

Electrosurgical ablation system (RF + heated saline infusion)

An electrosurgical generator platform engineered to deliver controlled radiofrequency energy concurrently with heated saline infusion via a catheter or needle electrode to produce local thermal coagulation and ablation.

Percutaneous porous-electrode ablation needle (16 gauge)

A 16-gauge percutaneous needle with a porous metal electrode designed for creating large, uniform soft-tissue lesions (reported capability to create ≈5 cm lesions in ex vivo liver).

Retractable-needle endocardial ablation catheter (needle-based catheter)

Catheter with a retractable fine-gauge needle designed for endocardial myocardial penetration to deliver RF plus heated saline infusion enabling transmural lesions for treatment of ventricular arrhythmias.


Services

Design and execution of investigator-led early feasibility studies for catheter-based ablation of VT at multi-center clinical sites.

Preclinical in vivo and ex vivo testing services including lesion creation, growth characterization, imaging correlation (MRI, ICE), histology, and microemboli assessment in large-animal models.

Preparation and execution of regulatory activities for medical devices and adjunct materials, including 510(k) submissions, IDE applications, and coordination for device designations and marketing clearances.

Expertise Areas

  • Ventricular tachycardia ablation
  • Soft-tissue thermal ablation for solid tumors
  • Preclinical lesion development and validation
  • Early feasibility clinical trials (medical devices)
  • Show More (3)

Key Technologies

  • Saline-enhanced radiofrequency ablation
  • Electrosurgical RF generator with synchronized fluid infusion
  • Retractable-needle catheter delivery
  • Porous metal electrode needle design
  • Show More (4)

News & Updates

The company received a $3 million NIH grant to test its SERF ablation system for treating ventricular tachycardia, aiming to improve efficacy and reduce costs compared to current therapies.

The company announced FDA approval for clinical trials of its SERF ablation system for VT, marking a significant step towards potential market approval.

The company completed a preclinical study demonstrating the feasibility of its pulsed field ablation technology.

The company received FDA breakthrough device designation for its SERF ablation system aimed at treating ventricular tachycardia.

The company's ablation system received FDA 510(k) clearance for soft tissue coagulation and ablation during various surgical procedures.

The SERF ablation system was granted FDA breakthrough device designation for VT treatment.


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