Theradaptive
Theradaptive is dedicated to developing innovative therapeutics through advanced protein engineering, aiming to improve the delivery and efficacy of treatments for patients suffering from debilitating conditions related to tissue damage. Their mission is to create safer and more effective therapeutics that address unmet medical needs, particularly in the fields of vascular, soft tissue, and orthopedic repair.
Industries
N/A
Products
Investigational spinal fusion implant with engineered material-binding protein
An investigational spinal fusion graft system that incorporates an engineered material-binding bone-regenerative protein to be placed within spinal fusion cages to promote bone growth while limiting off-target effects.
Engineered material-binding bone-regenerative protein
A recombinant protein variant engineered to retain bone-regenerative activity while binding with high affinity to a range of implant materials and carriers to enable targeted, durable delivery.
Investigational spinal fusion implant with engineered material-binding protein
An investigational spinal fusion graft system that incorporates an engineered material-binding bone-regenerative protein to be placed within spinal fusion cages to promote bone growth while limiting off-target effects.
Engineered material-binding bone-regenerative protein
A recombinant protein variant engineered to retain bone-regenerative activity while binding with high affinity to a range of implant materials and carriers to enable targeted, durable delivery.
Services
Partnered development and co-development collaborations
Collaborative programs with device manufacturers and research organizations to integrate engineered material-binding proteins with implants and carriers for regenerative applications.
Clinical trial design and operational support for implant-delivered biologics
Design and conduct of early-phase randomized clinical trials to assess safety and dosing of implant-delivered engineered proteins, including site coordination and patient follow-up schedules.
Partnered development and co-development collaborations
Collaborative programs with device manufacturers and research organizations to integrate engineered material-binding proteins with implants and carriers for regenerative applications.
Clinical trial design and operational support for implant-delivered biologics
Design and conduct of early-phase randomized clinical trials to assess safety and dosing of implant-delivered engineered proteins, including site coordination and patient follow-up schedules.
Expertise Areas
- Protein engineering for material-binding therapeutics
- Regenerative medicine and osteobiologics
- Preclinical large-animal orthopedic models
- Clinical trial management for implantable biologic-delivery devices
Key Technologies
- Computational protein design
- In vitro screening for material affinity
- Recombinant protein expression and purification
- Implant/device surface coating via adsorption