The NNT Group
Web-based resource that publishes concise, evidence-based clinician-focused summaries of therapeutic and diagnostic interventions. Content is organized by medical specialty and physiologic system, uses a documented editorial process and a four-level benefit–harm rating, reports absolute effect measures (for example, number-needed-to-treat and absolute risk differences), and maintains permanent, date-stamped single-topic review pages with links to source literature and searchable taxonomy-driven indexing.
Industries
Nr. of Employees
small (1-50)
Products
Curated single-topic therapy review pages
Single-topic web pages summarizing evidence for individual interventions, reporting numeric absolute effect measures, applying a standardized rating, and linking to primary sources; organized by specialty and physiologic system.
Indexed diagnostic accuracy review pages
Indexed reviews summarizing diagnostic test operating characteristics and clinical utility, presenting likelihood ratios and other measures to inform diagnostic decision-making; organized by specialty and physiologic system.
Specialty- and system-indexed archive
A browsable index of therapy and diagnostic reviews organized by medical specialty and physiologic system, providing curated lists and historical entries for many clinical topics.
theNNT Rating System
A framework and rating system developed by a group of physicians to evaluate therapies based on patient-important benefits and harms, as well as diagnostics by patient sign, symptom, lab test, or study.
The NNT Intervention Quiz
An interactive quiz designed to compare your ratings of medical interventions with those of The NNT Group, based on their evidence summaries and interpretations.
Tissue Plasminogen Activator (tPA) For Acute Ischemic Stroke
A review summary of thrombolytics for acute ischemic stroke focusing on the uncertainty in net benefits and harms based on systematic reviews and meta-analyses of randomized trials.
Curated single-topic therapy review pages
Single-topic web pages summarizing evidence for individual interventions, reporting numeric absolute effect measures, applying a standardized rating, and linking to primary sources; organized by specialty and physiologic system.
Indexed diagnostic accuracy review pages
Indexed reviews summarizing diagnostic test operating characteristics and clinical utility, presenting likelihood ratios and other measures to inform diagnostic decision-making; organized by specialty and physiologic system.
Specialty- and system-indexed archive
A browsable index of therapy and diagnostic reviews organized by medical specialty and physiologic system, providing curated lists and historical entries for many clinical topics.
theNNT Rating System
A framework and rating system developed by a group of physicians to evaluate therapies based on patient-important benefits and harms, as well as diagnostics by patient sign, symptom, lab test, or study.
The NNT Intervention Quiz
An interactive quiz designed to compare your ratings of medical interventions with those of The NNT Group, based on their evidence summaries and interpretations.
Tissue Plasminogen Activator (tPA) For Acute Ischemic Stroke
A review summary of thrombolytics for acute ischemic stroke focusing on the uncertainty in net benefits and harms based on systematic reviews and meta-analyses of randomized trials.
Services
Preparation and web publication of concise clinician-focused summaries of randomized trials and systematic reviews emphasizing patient-important outcomes and absolute effect measures, with standardized benefit–harm ratings.
Online tutorials and explanatory materials focused on interpreting absolute effect measures and the number-needed-to-treat concept for clinicians and learners.
Preparation and web publication of concise clinician-focused summaries of randomized trials and systematic reviews emphasizing patient-important outcomes and absolute effect measures, with standardized benefit–harm ratings.
Online tutorials and explanatory materials focused on interpreting absolute effect measures and the number-needed-to-treat concept for clinicians and learners.
Expertise Areas
- Concise clinical evidence synthesis and point-of-care summaries
- Quantitative clinical decision metrics (absolute effects, NNT/NNH)
- Diagnostic accuracy assessment using likelihood ratios
- Editorial governance and conflict-of-interest controls
Key Technologies
- Web-based searchable content management with taxonomy and tagging
- Calculation of absolute effect sizes (absolute risk differences, NNT/NNH)
- Likelihood-ratio analysis for diagnostic accuracy
- Systematic review appraisal and selective evidence synthesis methods
News & Updates
Summary: Alpha-lipoic acid shows little to no benefit over placebo for improving symptoms or impairment.
Summary: Testosterone replacement therapy shows no clear benefit over placebo.
Summary: Sustained-release naltrexone reduces illicit opioid use compared to standard care but shows slightly worse outcomes than opioid agonists.
Summary: Systematic review of randomized trials found video laryngoscopy reduced time to intubation and lowered the risk of oxygen desaturation <90% compared with fiberoptic bronchoscopy; heterogeneity limits generalizability.
Summary: Alpha-lipoic acid shows little to no benefit over placebo for improving symptoms or impairment.
Summary: Testosterone replacement therapy shows no clear benefit over placebo.
Summary: Sustained-release naltrexone reduces illicit opioid use compared to standard care but shows slightly worse outcomes than opioid agonists.
Summary: Systematic review of randomized trials found video laryngoscopy reduced time to intubation and lowered the risk of oxygen desaturation <90% compared with fiberoptic bronchoscopy; heterogeneity limits generalizability.