Tempris
Tempris is a leader in wireless, battery-free product temperature control technology for lyophilization in pharmaceutical and biotech applications. With over 15 years of experience, Tempris connects lab, tech transfer, and GMP production through an identical temperature profile, enabling faster product launches, lower costs, and standardized global processes. Their innovative solutions include real-time temperature monitoring, hot and cold spot detection, cycle optimization, predictive endpoint determination, and the new LyoCLC® software for endpoint prediction, supporting regulatory compliance and process efficiency.
Industries
Nr. of Employees
small (1-50)
Products
Battery-free in-product RF temperature sensor
Passive temperature sensor using a quartz resonator whose frequency shifts with temperature; energized by an interrogation RF carrier and designed for insertion into vials, syringes, trays and other primary containers.
RF interrogation unit with spectral analysis and automation interfaces
Receiver and interrogation unit that decodes sensor frequency deviations, performs spectral analysis to detect interference and can auto-switch channels; provides LAN/PoE and automation/SCADA interfaces for industrial integration.
Validated monitoring and visualization software with electronic-records export
Software that controls the interrogation unit, records and visualizes temperature data (including 3D/digital-twin views), and exports datasets in formats suitable for regulatory submissions and audit trails.
Closed-loop endpoint prediction and control module
Algorithmic module implementing data transformation (log-linearization), regression-based endpoint detection, fit-quality assessment, iterative base-temperature optimization and ML-assisted control recommendations for primary-drying endpoint determination.
Hygienic antenna assemblies for laboratory and production chambers
Antenna assemblies sized for laboratory doors up to full production chambers; production variants are designed for hygienic installation and compatibility with steam/sterilization-in-place routines.
Sensor accessories and consumables for reproducible placement
Mechanical accessories and disposable components (piercing tools, centering devices, disposable antennas, sensor holders) to ensure reproducible placement, safe handling and support for automated workflows; materials compatible with GMP and autoclaving where applicable.
Battery-free in-product RF temperature sensor
Passive temperature sensor using a quartz resonator whose frequency shifts with temperature; energized by an interrogation RF carrier and designed for insertion into vials, syringes, trays and other primary containers.
RF interrogation unit with spectral analysis and automation interfaces
Receiver and interrogation unit that decodes sensor frequency deviations, performs spectral analysis to detect interference and can auto-switch channels; provides LAN/PoE and automation/SCADA interfaces for industrial integration.
Validated monitoring and visualization software with electronic-records export
Software that controls the interrogation unit, records and visualizes temperature data (including 3D/digital-twin views), and exports datasets in formats suitable for regulatory submissions and audit trails.
Closed-loop endpoint prediction and control module
Algorithmic module implementing data transformation (log-linearization), regression-based endpoint detection, fit-quality assessment, iterative base-temperature optimization and ML-assisted control recommendations for primary-drying endpoint determination.
Hygienic antenna assemblies for laboratory and production chambers
Antenna assemblies sized for laboratory doors up to full production chambers; production variants are designed for hygienic installation and compatibility with steam/sterilization-in-place routines.
Sensor accessories and consumables for reproducible placement
Mechanical accessories and disposable components (piercing tools, centering devices, disposable antennas, sensor holders) to ensure reproducible placement, safe handling and support for automated workflows; materials compatible with GMP and autoclaving where applicable.
Services
Consulting, installation and execution of IQ/OQ protocols to qualify measurement hardware and integrate systems into production environments.
Calibration services traceable to standards with issuance of calibration certificates and scheduled preventive maintenance (on-site and remote options).
Operator and technical training plus remote support for hardware and software to ensure correct system operation and data handling.
Support for validation activities, preparation of Part 11–ready datasets and documentation used in regulatory submissions and audits.
Temporary rental of measurement systems and tailored service contracts to provide monitoring capacity and local support during development or production needs.
Consulting, installation and execution of IQ/OQ protocols to qualify measurement hardware and integrate systems into production environments.
Calibration services traceable to standards with issuance of calibration certificates and scheduled preventive maintenance (on-site and remote options).
Operator and technical training plus remote support for hardware and software to ensure correct system operation and data handling.
Support for validation activities, preparation of Part 11–ready datasets and documentation used in regulatory submissions and audits.
Temporary rental of measurement systems and tailored service contracts to provide monitoring capacity and local support during development or production needs.
Expertise Areas
- Real-time product temperature monitoring for lyophilization
- Process Analytical Technology (PAT) for freeze-drying
- Lyophilization cycle development, optimization and scale-up/transfer
- Closed-loop endpoint detection and process control algorithms
Key Technologies
- Battery-free RF temperature sensing (resonant quartz-based)
- RF backscatter interrogation and spectrum analysis
- 2.4 GHz sensor interrogation and multi-antenna systems
- Log-transformation and linear regression for exponential-phase linearization
News & Updates
A webinar demonstrating how Tempris technology simplifies lyophilization process development and scale-up.
Meet Tempris at the pharmaceutical industry event in Biarritz, France, October 7-9, 2025.
Visit Tempris at the Lyophilization conference in Cologne, October 21-23, 2025.
An article showcasing how Tempris technology shortens development timelines and improves process control.
Discussion of how Tempris enables real-time, non-intrusive temperature measurement during lyophilization.
Comparison of new Tempris sensor designs with traditional thermocouples, validating their applicability.
A webinar demonstrating how Tempris technology simplifies lyophilization process development and scale-up.
Meet Tempris at the pharmaceutical industry event in Biarritz, France, October 7-9, 2025.
Visit Tempris at the Lyophilization conference in Cologne, October 21-23, 2025.
An article showcasing how Tempris technology shortens development timelines and improves process control.
Discussion of how Tempris enables real-time, non-intrusive temperature measurement during lyophilization.
Comparison of new Tempris sensor designs with traditional thermocouples, validating their applicability.