TargImmune Therapeutics


Privately held Swiss biotechnology company (Basel) developing a targeted nucleic acid delivery platform that uses synthetic nanoparticles to deliver interchangeable nucleic acid therapeutics systemically to solid tumours. The platform aims to induce apoptosis and modulate immune responses in cancer cells and is being advanced through preclinical GLP/toxicology studies toward IND/CTA filing and first-in-human studies.

Industries

Biotechnology
Health Care
Pharmaceutical
Pharmaceutical Manufacturing

Nr. of Employees

small (1-50)

TargImmune Therapeutics


Patents

Chimeric proteins for targeting dsRNA

US-11912747-B2

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Systems and methods for automatically generating a data center network mapping for automated alarm consolidation

US-11743104-B2

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Castration resistant prostate cancer

US-11679160-B2

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Method of treating cancer

US-11298376-B2

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Polyplex of double-stranded RNA and polymeric conjugate

US-10543232-B2

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Polyethyleneimine polyethyleneglycol vectors

US-10278991-B2

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Products

TAR001

Lead targeted nucleic acid therapeutic candidate that targets epidermal growth factor receptor (EGFR) to deliver synthetic dsRNA to tumours overexpressing the receptor; advanced toward IND/CTA and first-in-human studies.

TAR002

Second platform-based nucleic acid therapeutic candidate in preclinical development (portfolio compound).

TAIMs

Targeted apoptosis and immune modulators utilizing synthetic nanoparticles to deliver interchangeable nucleic acid therapeutics directly on target.

TAR003

Pipeline candidate molecule under the TAIM development programme focusing on a key receptor target.

Expertise Areas

  • Targeted nucleic acid delivery
  • Oncology therapeutics for solid tumours
  • Preclinical development and GLP toxicology
  • IND/CTA regulatory readiness
  • Show More (2)

Key Technologies

  • Targeted nanoparticle delivery
  • Synthetic double-stranded RNA therapeutics (Poly-IC)
  • Receptor-specific targeting moieties (e.g., EGFR-directed delivery)
  • Systemic nucleic acid delivery to primary and metastatic tumours
  • Show More (1)

News & Updates

Announcement of completion of GLP toxicology studies and appointment of a Head of Technical Development to support progression toward clinical studies and CMC/scale-up.

Appointment of a Chief Medical Officer to support clinical development and preparation for IND/CTA and human studies.

Completed a CHF 17.7 million financing round and announced appointment of a new Chief Executive Officer to lead clinical advancement.

Announcement of a full-time Chief Financial Officer to guide financial strategy and funding options.

Profile and coverage describing the company's approach to harnessing antiviral defence mechanisms via targeted nucleic acid therapeutics.

Completed GLP-compliant toxicology studies supporting a path to human studies.

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