Sudhin Biopharma Co.
Developer and supplier of inclined/compact settler technologies and single-use disposable settling devices for bioprocessing. Focus areas include selective cell retention for perfusion bioreactors, primary clarification of cell culture fluid, gentle harvesting and concentration of cell therapy products, and a perfusion platform for recombinant protein production in Pichia pastoris. Maintains an active patent portfolio on particle settling devices and collaborates with academic and Manufacturing USA consortia for scale-up and application testing.
Industries
Nr. of Employees
small (1-50)
Sudhin Biopharma Co.
Patents
Products
Inclined/compact settler devices — 75 mm series (250 mL–2 L)
Clear polycarbonate inclined settler modules with multiple cone count geometries and configurable top/bottom port options for small-scale clarification and selective retention; available internal volumes ~241 mL to ~1995 mL.
Inclined/compact settler devices — 150 mm series (3.5 L–5.0 L)
Intermediate-scale settler modules with stainless steel stands and top central ports for clarified effluent; internal volumes typically 3.5 L and 5.0 L.
Inclined/compact settler devices — 300 mm series (~17–24 L)
Largest currently offered settler modules in transparent polycarbonate (~17.4 L) and stainless steel (~23.8 L) with larger settling areas for higher-volume clarified harvests.
BioSettler 75-1500
A BioSettler with a cylindrical diameter of 75 mm, internal volume of 1458 mL, settling area of 1395 cm2, 44 cones, and total height of 494 mm, fabricated in clear polycarbonate for visual inspection during operation.
BioSettler 75-250
A BioSettler with a cylindrical diameter of 75 mm, internal volume of 241 mL, settling area of 217 cm2, 6 cones, and total height of 168 mm, fabricated in clear polycarbonate for visual inspection during operation.
BioSettler 75-500
A BioSettler with a cylindrical diameter of 75 mm, internal volume of 498 mL, settling area of 465 cm2, 14 cones, and total height of 236 mm, fabricated in clear polycarbonate for visual inspection during operation.
Inclined/compact settler devices — 75 mm series (250 mL–2 L)
Clear polycarbonate inclined settler modules with multiple cone count geometries and configurable top/bottom port options for small-scale clarification and selective retention; available internal volumes ~241 mL to ~1995 mL.
Inclined/compact settler devices — 150 mm series (3.5 L–5.0 L)
Intermediate-scale settler modules with stainless steel stands and top central ports for clarified effluent; internal volumes typically 3.5 L and 5.0 L.
Inclined/compact settler devices — 300 mm series (~17–24 L)
Largest currently offered settler modules in transparent polycarbonate (~17.4 L) and stainless steel (~23.8 L) with larger settling areas for higher-volume clarified harvests.
BioSettler 75-1500
A BioSettler with a cylindrical diameter of 75 mm, internal volume of 1458 mL, settling area of 1395 cm2, 44 cones, and total height of 494 mm, fabricated in clear polycarbonate for visual inspection during operation.
BioSettler 75-250
A BioSettler with a cylindrical diameter of 75 mm, internal volume of 241 mL, settling area of 217 cm2, 6 cones, and total height of 168 mm, fabricated in clear polycarbonate for visual inspection during operation.
BioSettler 75-500
A BioSettler with a cylindrical diameter of 75 mm, internal volume of 498 mL, settling area of 465 cm2, 14 cones, and total height of 236 mm, fabricated in clear polycarbonate for visual inspection during operation.
Services
Supply of single-use disposable inclined/compact settler devices in multiple sizes for clarification, selective cell retention, and cell therapy applications; availability for beta testing and pilot use.
Collaborative R&D and joint development of settler-enabled processes for clarification, cell therapy harvest, AAV/gene therapy vector production, and extractive fermentations.
Production and sale of small quantities of recombinant proteins and growth factors produced in Pichia pastoris for research use (examples: brazzein, human albumin, hFGF2, hEGF, hIGF1).
Supply of single-use disposable inclined/compact settler devices in multiple sizes for clarification, selective cell retention, and cell therapy applications; availability for beta testing and pilot use.
Collaborative R&D and joint development of settler-enabled processes for clarification, cell therapy harvest, AAV/gene therapy vector production, and extractive fermentations.
Production and sale of small quantities of recombinant proteins and growth factors produced in Pichia pastoris for research use (examples: brazzein, human albumin, hFGF2, hEGF, hIGF1).
Expertise Areas
- Cell retention technologies for perfusion bioreactors
- Primary clarification of cell culture fluid
- Cell therapy product concentration and harvest workflows
- Perfusion fermentation for recombinant protein production (microbial)
Key Technologies
- Inclined/lamellar settling surfaces
- Compact cell settler geometries
- Single-use disposable plastic bioprocess devices
- Perfusion bioreactor integration and flow control
News & Updates
Oral presentation on use of inclined/settler devices to recycle organoids and remove single cells and spent media.
Selected for collaborative project with BioMADE and collaborators to test settler use for breaking oil–water emulsions in extractive fermentations; project funding noted in news updates.
Launch and demonstration of single-use compact settler as part of a NIIMBL-funded project to scale-up single-use settlers for clarification and perfusion applications.
Poster and experimental data showing acidification of cell culture fluid within a settler for combined primary clarification and viral inactivation with high product recovery and reduced turbidity.
Awarded a NIIMBL Quick Start Project to fund fabrication and characterization of single-use settlers in multiple sizes for perfusion and clarification applications.
Received R&D funding and collaboration to demonstrate settler performance for in situ product extraction and emulsion separation (selected for BioMADE project; Sudhin portion noted).
Oral presentation on use of inclined/settler devices to recycle organoids and remove single cells and spent media.
Selected for collaborative project with BioMADE and collaborators to test settler use for breaking oil–water emulsions in extractive fermentations; project funding noted in news updates.
Launch and demonstration of single-use compact settler as part of a NIIMBL-funded project to scale-up single-use settlers for clarification and perfusion applications.
Poster and experimental data showing acidification of cell culture fluid within a settler for combined primary clarification and viral inactivation with high product recovery and reduced turbidity.
Awarded a NIIMBL Quick Start Project to fund fabrication and characterization of single-use settlers in multiple sizes for perfusion and clarification applications.
Received R&D funding and collaboration to demonstrate settler performance for in situ product extraction and emulsion separation (selected for BioMADE project; Sudhin portion noted).