Structure Therapeutics


Clinical-stage biopharmaceutical company developing orally available small-molecule therapeutics for chronic metabolic, obesity-related and cardiopulmonary diseases. The organization applies structure-based drug design, GPCR structural biology, computational chemistry and data science to discover and advance oral small-molecule candidates from discovery through early clinical development. The company publishes peer-reviewed structural biology and translational pharmacology work and presents data at scientific conferences.

Industries

Biotechnology
Health Care
Medical
Pharmaceutical
Product Research
Pharmaceutical and biotechnology
Biotechnology Research

Nr. of Employees

medium (51-250)

Structure Therapeutics

South San Francisco, California, United States


Patents

Heterocyclic GLP-1 agonists

US-12595264-B2

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Heterocyclic GLP-1 agonists

US-12552791-B2

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Heterocyclic GLP-1 agonists

US-12528781-B2

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Heterocyclic GLP-1 agonists

US-12221442-B2

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Compounds and compositions for treating conditions associated with APJ receptor activity

US-11944622-B2

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Heterocyclic GLP-1 agonists

US-11926626-B2

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Products

Clinical-stage portfolio of orally available small-molecule therapeutics

A portfolio of oral, non-peptide small-molecule candidates designed for chronic metabolic, obesity-related and cardiopulmonary conditions; advanced through preclinical studies into early clinical trials.

Expertise Areas

  • Structure-based drug discovery for GPCRs
  • Computational chemistry and physics-based modeling
  • Medicinal chemistry and SAR optimization
  • High-throughput structural biology and crystallography
  • Show More (6)

Key Technologies

  • Structure-based drug design
  • Physics-based computational modeling
  • Molecular dynamics / physics-driven methods
  • X-ray crystallography
  • Show More (10)

News & Updates

Announcement reporting positive clinical data across oral small-molecule programs for chronic weight management.


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