Stemloop, Inc.
Stemloop is dedicated to unlocking the power of biology to sense and respond to the world's challenges through innovative biosensor technology. They develop high-performance, scalable biosensors for applications in environmental monitoring, agriculture, manufacturing, health, and wellness. Their proprietary platforms, ROSALIND™ and Plover Pipeline™, enable rapid, cost-effective detection of small molecules and contaminants, transforming chemical testing and analysis. With a mission to address large-scale, unmet testing needs, Stemloop leverages synthetic biology, AI, and machine learning to create tailored biosensor solutions that provide real-time, actionable chemical data, ultimately aiming to revolutionize how we measure and respond to chemical and biological signals across various industries.
Industries
Nr. of Employees
small (1-50)
Products
Lead detection lateral-flow biosensor kit (soluble lead, ≥5 ppb)
Single-use lateral-flow style biosensor kit designed to detect soluble lead in drinking water with a visual band readout; intended for distribution via drinking water providers.
Custom biosensor assay formats (single-use to high-throughput well-plates)
Custom-developed biosensor assays delivered in multiple formats, including single-use test kits for field use and well-plate formats for laboratory high-throughput screening.
Lead detection lateral-flow biosensor kit (soluble lead, ≥5 ppb)
Single-use lateral-flow style biosensor kit designed to detect soluble lead in drinking water with a visual band readout; intended for distribution via drinking water providers.
Custom biosensor assay formats (single-use to high-throughput well-plates)
Custom-developed biosensor assays delivered in multiple formats, including single-use test kits for field use and well-plate formats for laboratory high-throughput screening.
Services
End-to-end development of custom biosensors tuned for target analyte, detection threshold, specificity, and preferred output format.
Large-scale discovery and functional characterization workflows to generate datasets for sensor selection and machine-learning model training.
Coordination with ISO-certified third-party manufacturers to scale production of biosensor reagents and test kits.
User instructions, instructional media, FAQs, and support channels for running and reporting results from deployed test kits.
End-to-end development of custom biosensors tuned for target analyte, detection threshold, specificity, and preferred output format.
Large-scale discovery and functional characterization workflows to generate datasets for sensor selection and machine-learning model training.
Coordination with ISO-certified third-party manufacturers to scale production of biosensor reagents and test kits.
User instructions, instructional media, FAQs, and support channels for running and reporting results from deployed test kits.
Expertise Areas
- Biosensor assay development
- Cell-free synthetic biology
- Nucleic-acid circuit design
- Protein engineering and recombinant expression
Key Technologies
- Cell-free in vitro transcription systems
- RNA aptamer reporters
- DNA/RNA strand-displacement circuits
- Transcription factor-based sensing
News & Updates
Stemloop received catalytic funding from DARPA to develop machine learning models for biosensor discovery, aiming to reduce development time and enhance biosensor capabilities.
Stemloop announced the formation of an advisory board including James J. Collins and Andrew Ellington to bolster its biosensor research and platform development.
A patent application describing the use of cell-free biosensors for rapid chemical detection in lateral flow formats.
A publication in Nature Chemical Biology on interfacing biosensors with DNA nanotechnology for fine-tuning reactions.
A Nature Biotechnology article on using RNA-based biosensors for water quality monitoring.
Stemloop received catalytic funding from DARPA to develop machine learning models for biosensor discovery, aiming to reduce development time and enhance biosensor capabilities.
Stemloop announced the formation of an advisory board including James J. Collins and Andrew Ellington to bolster its biosensor research and platform development.
A patent application describing the use of cell-free biosensors for rapid chemical detection in lateral flow formats.
A publication in Nature Chemical Biology on interfacing biosensors with DNA nanotechnology for fine-tuning reactions.
A Nature Biotechnology article on using RNA-based biosensors for water quality monitoring.