SOPHiA GENETICS


Provider of a cloud-native analytics platform that applies machine learning to integrate and analyze multimodal clinical data (genomics, imaging and clinical records). Offers standardized bioinformatics pipelines, clinical workflows and reporting, regulatory-compliant data handling, and professional services for assay co-development, analytical validation, and deployment of scalable diagnostic and real-world evidence solutions.

Industries

Artificial Intelligence
Artificial Intelligence (AI)
Big Data
Bioinformatics
Biotechnology
Genetics
Health Care
Life Science
Medical
Software
Therapeutics
Biotechnology Research

Nr. of Employees

large (251-1000)

SOPHiA GENETICS


Patents

Methods for detecting copy-number variations in next-generation sequencing

US-12731658-B2

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Methods for DNA library generation to facilitate the detection and reporting of low frequency variants

US-12674158-B2

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Methods for detecting variants in next-generation sequencing genomic data

US-12633377-B2

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Methods for detecting variants in next- generation sequencing genomic data

US-12573472-B2

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Methods for asymmetric DNA library generation and optionally integrated duplex sequencing

US-12297490-B2

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Capture probes and uses thereof

US-12247255-B2

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Products

IVD-certified genomics analytics for defined indications

In vitro diagnostic software solutions certified for specific oncology and hereditary indications in markets recognizing those certifications; the same platform can be used in Research Use Only mode where applicable.

Research-use analytics and variant-interpretation modules

Research-use-only analytics modules and interpretation tools for exome and genome analysis, variant review and knowledge-base driven interpretation for research and laboratory use.


Services

Cloud-hosted analytics and interpretation services for genomic, imaging and multimodal clinical data delivered to healthcare institutions, clinical laboratories and biopharma partners.

Collaborative programs with academic, clinical and industry partners to co-develop NGS assays, clinical trial assays and companion diagnostics, including support for validation and clinical translation.

Consulting services to support clinical deployment, analytical validation studies, workflow optimization and regulatory/quality system preparation for diagnostic assays and analytic software.

Expertise Areas

  • Clinical genomics and variant interpretation
  • Precision oncology analytics
  • Bioinformatics pipeline development for NGS and RNA-seq
  • Liquid biopsy and ctDNA analysis
  • Show More (8)

Key Technologies

  • Next-generation sequencing (NGS) analysis
  • RNA-sequencing (RNA-seq) analysis
  • Machine learning and deep learning for biomedical data
  • Cloud-native analytics and distributed compute (CPU/GPU)
  • Show More (7)

News & Updates

In-person forum at ESMO 2026 focused on liquid biopsy, decentralized testing, next-generation biomarkers, strategic partnerships and validation practices in precision oncology.

Announcement of a strategic collaboration to combine AI-powered analytics with clinical expertise to co-develop NGS oncology tests, RNA-seq bioinformatics and joint R&D programs.

Announcement that the analytics platform received certification under the European IVDR, validating the platform's diagnostic mode and confirming compliance with IVDR requirements for genetic analysis in markets recognizing IVDR.

Expansion of a collaboration using AI and multimodal data to improve detection of biomarkers and support precision oncology research and clinical development.

Partnership combining centralized companion diagnostic regulatory expertise with a decentralized, data-driven analytics platform to co-develop liquid biopsy CDx offerings.

Partnership with a local laboratory and market-access partner to enable broader liquid biopsy testing and support CDx commercialization in Japan.

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