SonoThera
SonoThera is developing an ultrasound-mediated nonviral gene therapy platform and therapies to provide patients with the next generation of genetic medicines. Their technology platform aims to overcome significant barriers in gene therapy such as safety, efficacy, biodistribution, and high costs of goods, using sonoporation to deliver genetic payloads non-invasively and selectively to a wide range of organs.
Industries
Nr. of Employees
small (1-50)
SonoThera
South San Francisco, California, United States
Patents
Products
Ultrasound-guided nonviral gene delivery platform
A therapeutic platform that uses microbubble-mediated sonoporation and optimized acoustic profiles with clinical ultrasound systems to deliver diverse nucleic acid payloads to targeted organs without viral vectors.
RIPPLE
Proprietary, nonviral, non-invasive, immune stealth ultrasound-mediated delivery technology enabling targeted biodistribution of genetic medicines.
Ultrasound-guided nonviral gene delivery platform
A therapeutic platform that uses microbubble-mediated sonoporation and optimized acoustic profiles with clinical ultrasound systems to deliver diverse nucleic acid payloads to targeted organs without viral vectors.
RIPPLE
Proprietary, nonviral, non-invasive, immune stealth ultrasound-mediated delivery technology enabling targeted biodistribution of genetic medicines.
Services
Platform optimization, IND-enabling preclinical studies, and early-stage manufacturing/process development support for nucleic acid therapeutics.
Collaborative research partnerships and licensing arrangements for microbubble contrast agents and co-development to enable ultrasound-mediated delivery.
Platform optimization, IND-enabling preclinical studies, and early-stage manufacturing/process development support for nucleic acid therapeutics.
Collaborative research partnerships and licensing arrangements for microbubble contrast agents and co-development to enable ultrasound-mediated delivery.
Expertise Areas
- Nonviral gene delivery
- Ultrasound-guided therapeutic delivery
- Preclinical in vivo pharmacology
- Platform process development and early manufacturing
Key Technologies
- Microbubble-mediated sonoporation
- Clinical ultrasound hardware integration
- Acoustic profile optimization
- Nucleic acid therapeutic delivery (plasmid, mRNA, oligonucleotides)
News & Updates
A study on sonoporation for augmenting chemotherapy in pancreatic cancer.
A review on advances in ultrasound-mediated gene therapy using microbubbles.
An article on ultrasound-mediated targeted drug delivery.
A study on sonoporation for augmenting chemotherapy in pancreatic cancer.
A review on advances in ultrasound-mediated gene therapy using microbubbles.
An article on ultrasound-mediated targeted drug delivery.