SonoThera


SonoThera is developing an ultrasound-mediated nonviral gene therapy platform and therapies to provide patients with the next generation of genetic medicines. Their technology platform aims to overcome significant barriers in gene therapy such as safety, efficacy, biodistribution, and high costs of goods, using sonoporation to deliver genetic payloads non-invasively and selectively to a wide range of organs.

Industries

biopharma
biotechnology
genetics
medical

Nr. of Employees

small (1-50)

SonoThera

San Francisco, California, United States, North America


Products

Ultrasound-guided nonviral gene delivery platform

A therapeutic platform that uses microbubble-mediated sonoporation and optimized acoustic profiles with clinical ultrasound systems to deliver diverse nucleic acid payloads to targeted organs without viral vectors.


Services

Preclinical development and early manufacturing support

Platform optimization, IND-enabling preclinical studies, and early-stage manufacturing/process development support for nucleic acid therapeutics.

Research collaborations and licensing of enabling agents

Collaborative research partnerships and licensing arrangements for microbubble contrast agents and co-development to enable ultrasound-mediated delivery.

Expertise Areas

  • Nonviral gene delivery
  • Ultrasound-guided therapeutic delivery
  • Preclinical in vivo pharmacology
  • Platform process development and early manufacturing
  • Show More (5)

Key Technologies

  • Microbubble-mediated sonoporation
  • Clinical ultrasound hardware integration
  • Acoustic profile optimization
  • Nucleic acid therapeutic delivery (plasmid, mRNA, oligonucleotides)
  • Show More (4)

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