SoniVie


SoniVie is a medical device company dedicated to developing innovative ultrasound-based denervation systems for treating hypertensive disorders, including resistant hypertension and pulmonary hypertension. Founded in 2014, the company has achieved significant milestones including FDA Breakthrough Device Designations, clinical trials, and a pending acquisition by Boston Scientific. Their flagship product, TIVUS, employs high-frequency ultrasound technology to safely and effectively perform renal and pulmonary denervation procedures, aiming to improve patient outcomes and address unmet medical needs.

Industries

health-care
health-diagnostics
medical

Nr. of Employees

small (1-50)

SoniVie

2 Haim Holtzman St, Rehovot 7670402, Israel


Patents

Tissue treatment

US-12539160-B2

View Details

Ultrasound transducer and uses thereof

US-12364501-B2

View Details

Devices and methods for reducing parasympathetic nerve activity in patients with a respiratory syndrome

US-12318638-B2

View Details

Method for treating secondary pulmonary hypertension

US-12274897-B2

View Details

Pulmonary hypertension treatment

US-12251582-B2

View Details

Method and/or apparatus for measuring renal denervation effectiveness

US-12201444-B2

View Details
View All Patents

Products

Intravascular ultrasound denervation system (catheter-based)

A catheter-based intravascular system that delivers high-frequency non-focused ultrasonic energy to ablate perivascular nerves while maintaining blood flow through the treated vessel; developed for renal and pulmonary denervation procedures.


Services

Planning and operating multicenter clinical studies (IDE-approved pilot and pivotal studies), providing site initiation and enrollment support, study monitoring, and clinical data collection for regulatory submissions.

Development and consolidation of intravascular ultrasound denervation platform technologies and associated intellectual property to enable multi-indication development.

Expertise Areas

  • Renal denervation procedures and clinical development
  • Pulmonary artery denervation for pulmonary hypertension
  • Platform development for multiorgan denervation (including lung denervation)
  • Clinical trial design and global trial execution (IDE and pivotal studies)
  • Show More (3)

Key Technologies

  • Intravascular therapeutic ultrasound
  • High-frequency non-focused ultrasound ablation
  • Catheter-based nerve ablation
  • Radial rapid-exchange catheter design (4Fr)
  • Show More (3)

News & Updates

Acquisition to expand interventional cardiology therapies with ultrasound-based renal denervation for hypertension.

SoniVie announced the appointment of Raymond W. Cohen as its chairman of the board.

SoniVie announced pilot results, FDA approval for the global THRIVE study, and progress in renal denervation.

SoniVie announced the last patient was treated in the REDUCED-1 pilot study for hypertension.

The company secured funding to support clinical and regulatory milestones for TIVUS.

Details about the acquisition of SoniVie by Boston Scientific to expand interventional cardiology therapies.

View All News

Similar organizations

Browse all ORGANIZATIONS

JOIN OUR MAILING LIST

Stay Connected with MTEC

Keep up with active and upcoming solicitations, MTEC news and other valuable information.