SetPoint Medical Corporation


SetPoint Medical is dedicated to transforming the treatment of chronic autoimmune conditions through innovative bioelectronic medicine. Their platform utilizes targeted electrical stimulation of the vagus nerve to regulate inflammation and restore immunologic balance, offering a potentially safe, effective, and cost-efficient alternative to traditional drug therapies. The company is committed to evidence-based clinical research and developing advanced implantable neuromodulation devices to treat diseases such as rheumatoid arthritis, Crohn’s disease, and multiple sclerosis.

Industries

biotechnology
health-care
medical
therapeutics

Nr. of Employees

medium (51-250)


Patents

Batteryless implantable microstimulators

US-12296169-B2

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Vagus nerve stimulation to treat neurodegenerative disorders

US-12172017-B2

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Control of vagal stimulation

US-12121726-B2

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Closed-loop vagus nerve stimulation

US-11969253-B2

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Batteryless implantable microstimulators

US-11964150-B2

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Vagus nerve stimulation pre-screening test

US-11890471-B2

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Products

Implantable vagus nerve stimulator system

A system consisting of a miniaturized, implantable neurostimulator, a wireless charger, and a clinician tablet application designed to deliver targeted vagus nerve stimulation to modulate inflammatory pathways.


Services

Design and conduct of IDE-regulated clinical studies including pilot, feasibility, and randomized double-blind sham-controlled pivotal trials across multiple clinical sites.

Preclinical studies in animal models to evaluate mechanisms of action, effects on demyelination/remyelination, and to support clinical translation.

Managed vulnerability reporting and remediation coordination, including a public vulnerability disclosure program, tiered rewards, and encrypted reporting guidance.

Engineering and integration of implantable neurostimulator hardware, packaging, wireless charging, telemetry, and clinician-facing therapy management software.

Expertise Areas

  • Bioelectronic medicine
  • Neuromodulation and vagus nerve stimulation
  • Clinical trial management for investigational devices
  • Medical device development and miniaturized implant engineering
  • Show More (5)

Key Technologies

  • Vagus nerve stimulation
  • Implantable pulse generator (miniaturized neurostimulator)
  • Wireless charging for implants
  • Telemetry for implantable medical devices
  • Show More (4)

News & Updates

FDA approval for a pilot study to evaluate the neuroimmune modulation platform in multiple sclerosis patients.

Enrollment of the first patient in a pivotal clinical trial for rheumatoid arthritis treatment.

Data from clinical studies showing the effectiveness of vagus nerve stimulation in reducing RA symptoms.

An article discussing the advances in bioelectronic medicine and its potential to revolutionize treatment of inflammatory diseases.

Recognized by FierceMedicalDevices as one of the most promising private companies in med tech.


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