Rhygaze


Developer of optogenetic-based gene therapy approaches for vision restoration. The organization combines optogenetic protein engineering and gene delivery tools to install light-sensing function into target retinal cell types and advances programs from preclinical assay development through clinical translation. Headquarters in Basel, Switzerland and Philadelphia, PA, USA.

Industries

biotechnology
health-care
therapeutics

Nr. of Employees

small (1-50)

Rhygaze


Products

Optogenetic gene therapy platform for retinal photosensitization

A platform combining optogenetic proteins with gene delivery tools to confer light sensitivity to target retinal cell types for vision restoration.


Services

Non-clinical assay development and IND-enabling studies to support clinical progression of ophthalmic gene therapies.

Clinical translation, regulatory submission preparation, and program-level management for gene therapy candidates in ophthalmology.

Expertise Areas

  • Optogenetic therapy development
  • Retinal gene therapy
  • Clinical translation of gene therapies
  • Preclinical assay development and IND-enabling studies
  • Show More (3)

Key Technologies

  • Optogenetics
  • Gene delivery vectors (AAV-mediated delivery)
  • Preclinical assay development
  • IND-enabling study design
  • Show More (1)

News & Updates

Multiple team members were instrumental in the development, regulatory approval, and commercialization of a landmark retinal gene therapy that was the first gene therapy product approved by the U.S. FDA for a genetic disease.


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